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Fig. 4 | Critical Care

Fig. 4

From: Exploring the microvascular impact of red blood cell transfusion in intensive care unit patients

Fig. 4

Spearman’s rank correlation matrices for arachidonic acid (AA) and AA metabolites quantified by LC-MS/MS in the plasma of patients before and after transfusion (a). Blue and red indicate positive and negative correlations respectively and the color intensity the strength of the correlation. 14,15-DHET, 14,15-dihydroxyeicosatrienoic acid; 11,12-DHET, 11,12-dihydroxyeicosatrienoic acid; 8,9-DHET, 8,9-dihydroxyeicosatrienoic acid; 14,15-EET, 14,15-epoxyeicosatrienoic acid; 11,12-EET, 11,12-epoxyeicosatrienoic acid; 8,9-EET, 8,9-epoxyeicosatrienoic acid; 15-HETE, 15-hydroxyeicosatetraenoic acid; 12-HETE, 12-hydroxyeicosatetraenoic acid; 5-HETE, 5-hydroxyeicosatetraenoic acid; AA, arachidonic acid; NO2-AA, nitroarachidonate. *p < 0.05; **p < 0.01, ***p < 0.001. Given p values are adjusted using the Benjamini and Hochberg corrections. NO2AA/AA (b) and HETEs/AA (c) plasma level ratios before and after transfusion in both groups. HETEs is the sum of 5-HETE, 12-HETE, and 15-HETE

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