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Table 2 Patient characteristics and clinical outcomes

From: Machine learning versus physicians’ prediction of acute kidney injury in critically ill adults: a prospective evaluation of the AKIpredictor

 

Admission cohort

Day1 cohort

Day1+ cohort

N

252

238

195

AKI-23 by SCr and UO, n (%)

30 (12)

17 (7)

17 (9)

Time to AKI-23 by SCr and UO, hours from admission

27.1 (9.6–61.6)

39.7 (31.6–109.4)

39.7 (31.6–109.4)

AKI-23 by SCr, n (%)

23 (9)

13 (5)

13 (7)

Time to AKI-23 by SCr, hours from admission

28.3 (12.1–38.4)

37.1 (32.9–61.5)

37.1 (32.9–61.5)

ICU LOS, days

3 (2–7)

2 (2–6)

3 (2–7)

Demographics

 Age, year

65.5 (52.8–74.0)

65 (52–74)

66 (54–74)

 Male gender, n (%)

155 (61.5)

146 (61.3)

121 (62.1)

 Height, cm

171 (165–178)

171 (165–178)

171 (165–178)

 Weight, kg

75.2 (65.0–86.3)

75.0 (65.0–86.0)

75.0 (63.5–85.7)

 Diabetic, n (%)

6 (2.4)

5 (2.1)

3 (1.5)

 Baseline SCr, mg/dL

0.88 (0.73–1.05)

0.88 (0.73–1.04)

0.88 (0.73–1.06)

Clinical parameters

 Elective admission, n (%)

154 (61.1)

149 (62.6)

124 (63.6)

 Surgical category, n (%)

  Cardiac

103 (40.9)

98 (41.1)

85 (43.6)

  Transplant

7 (2.8)

7 (2.9)

7 (3.6)

  Others

92 (36.5)

86 (35.8)

71 (36.4)

 Medical category, n (%)

50 (19.8)

47 (19.8)

32 (16.4)

 Hemodynamic support at ICU admission, n (%)

  Pharmacological

165 (65.5)

158 (66.4)

140 (71.8)

  Mechanical

4 (1.6)

3 (1.3)

3 (1.5)

 Blood glucose at ICU admission, mg/dL

135 (113–155)

135 (114–155)

137 (116–160)

 Sepsis upon ICU admission, n (%)

20 (7.9)

18 (7.6)

16 (8.2)

 Maximum lactate on day 1, mg/dL

1.6 (1.1–2.4)

1.5 (1.1–2.3)

1.6 (1.1–2.4)

 Bilirubin on day 1, mg/dL

0.54 (0.37–0.84)

0.54 (0.37–0.83)

0.53 (0.38–0.83)

 Apache II score on day 1

14 (10–17)

13.5 (10–17)

14 (11–17)

 SOFA score on day 1

9 (5–11)

9 (5–11)

9 (6–12)

 SCr on day 1, md/dL,

0.87 (0.68–1.08)

0.87 (0.68–1.05)

0.88 (0.70–1.08)

Monitoring parametersa

 UO slope, mL/hour

−0.00014 (−0.00052 to 0.00034)

−0.00013 (−0.00051 to 0.00035)

−0.00014 (−0.00046 to 0.00032)

 Total amount of UO, mL/hour

1025 (770–1437)

1047 (789–1451)

1048 (495–1473)

 Blood pressure below 60 mmHg, min

10 (3–50)

10 (3–48)

11 (4–51)

 Blood pressure above average, min

644 (569–696)

647 (569–698)

655 (593–716)

 Dose of vasopressors, mg

2.7 (0–8.9)

2.7 (0–8.6)

4.3 (0–9.7)

  1. Data are reported as median (IQR) unless otherwise indicated
  2. Abbreviations: AKI acute kidney injury, ICU intensive care unit, IQR interquartile ranges, LOS length of stay, SCr serum creatinine, UO urine output
  3. aMeasured during the first 24 h of ICU stay