Table 1 Baseline characteristics and outcomes in the 124 study patients
Characteristics/outcomes | Direct-risk ARDS (n = 56) | Idiopathic/immune ARDS (n = 31) | Unilateral pneumonia (n = 37) | P* | P** |
|---|---|---|---|---|---|
Demographics | |||||
Age, years | 70 (63–77.8) | 66 (59–75) | 66 (58.5–76) | 0.19 | 0.39 |
Male, n (%) | 41 (73.2) | 16 (51.6) | 25 (67.6) | 0.044 | 0.13 |
Comorbidities, n (%) | |||||
IHD | 7 (12.5) | 3 (9.7) | 3 (8.1) | 1.00 | 0.78 |
CHF | 8 (14.3) | 3 (9.7) | 3 (8.1) | 0.74 | 0.62 |
Arrhythmia | 7 (12.5) | 2 (6.5) | 2 (5.4) | 0.48 | 0.43 |
COPD | 5 (8.9) | 2 (6.5) | 7 (18.9) | 1.00 | 0.22 |
CKD | 11 (19.6) | 6 (19.4) | 7 (18.9) | 1.00 | 0.99 |
CVD | 9 (16.1) | 3 (9.7) | 6 (13.2) | 0.53 | 0.66 |
Severity of illness | |||||
APACHE II score | 31 (25–35) | 23 (18–26) | 24 (19–29) | < 0.0001 | < 0.0001 |
SAPS II score | 60 (52–75) | 44 (27–52) | 48 (35–57) | < 0.0001 | < 0.0001 |
SOFA score | |||||
Day 1 | 9 (7.3–11) | 6 (5–8) | 7 (6–9) | < 0.0001 | < 0.0001 |
Maximum | 11 (8–14) | 7 (6–9) | 8 (7.0–10.5) | < 0.0001 | < 0.0001 |
PaO2/FIO2 ratio, day 1 | 127 (86.8–194) | 119 (75–170) | 192 (137–234) | 0.89 | 0.0035 |
Set PEEP (cmH2O), day 1 | 8 (5–10) | 8 (5–8) | 8 (5–10) | 0.58 | 0.86 |
Severity of ARDS | 0.29 | ||||
Mild | 13 (23.2) | 4 (12.9) | |||
Moderate | 23 (41.1) | 15 (48.4) | |||
Severe | 20 (35.7) | 12 (38.7) | |||
Prognosis | |||||
ICU days | 11 (8–18) | 10 (7–17) | 10 (6.5–14) | 0.82 | 0.45 |
Ventilator-free days | 9.5 (0–20) | 17 (0–22) | 18 (14–22) | 0.12 | 0.021 |
Mortality, n (%) | |||||
28 days | 12 (21.4) | 4 (12.9) | 1 (2.7) | 0.37 | 0.019 |
90 days | 17 (30.4) | 9 (29.0) | 1. (2.7) | 0.89 | 0.0007 |