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Fig. 1 | Critical Care

Fig. 1

From: Biomarker profiles of coagulopathy and alveolar epithelial injury in acute respiratory distress syndrome with idiopathic/immune-related disease or common direct risk factors

Fig. 1

Pulmonary coagulopathy, epithelial injury, and their related biomarkers in acute respiratory distress syndrome. Proinflammatory stimuli induce the expression and production of procoagulant and antifibrinolytic factors in different cell populations and epithelial/endothelial injury in the lung. AEC, alveolar epithelial cell; DAMPS, damage-associated molecular patterns; PAI-1, plasminogen activator inhibitor-1; PAMP, pathogen-associated molecular patterns; PRR, pattern recognition receptors; SP, surfactant protein; TAT, thrombin–antithrombin complex

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