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Table 3 Outcome measures in ARDS survivors from two multicenter cohort studies

From: Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)

Outcome measure

ALTOSa

n = 815

ICAPb

n = 186

IES-Rd at follow-up mean (SD)c

 3 months

n/a

1.1 (0.9)

 6 months

1.0 (0.9)

0.9 (0.8)

 12 months

1.0 (0.9)

0.9 (0.9)

 24 months

n/a

0.9 (0.9)

 36 months

n/a

0.8 (0.8)

 48 months

n/a

0.7 (0.9)

 60 months

n/a

0.7 (0.9)

 Across all time points

1 (0.9)

0.9 (0.9)

IES-6e at follow-up mean (SD)

 3 months

n/a

1.1 (0.9)

 6 months

1.1 (1.0)

0.9 (0.9)

 12 months

1.0 (1.1)

0.9 (0.9)

 24 months

n/a

0.9 (0.9)

 36 months

n/a

0.8 (0.9)

 48 months

n/a

0.7 (0.9)

 60 months

n/a

0.7 (0.9)

 Across all time points

1.1 (1.0)

0.8 (0.9)

External construct validity (related) mean (SD)f

 SF-36g Mental Health Domain

44.5 (14.3)

47.1 (13.1)

 SF-36g Mental Component Summary

45.3 (14.86)

47.2 (13.2)

 HADSh Anxiety

7.0 (5.1)

5.9 (4.7)

 HADSh Depression

6.0 (4.9)

5.1 (4.3)

 EQ-5D-3L Anxiety/Depression Item

1.7 (0.7)

1.6 (0.6)

External construct validity (unrelated) mean (SD)

 SF-36g Role Physical Subscale

38.5 (13.0)

39.6 (12.8)

 SF-36g Physical Function Subscale

37.0 (13.4)

38.3 (13.0)

 EQ-5D-3L Mobility Item

1.6 (0.5)

0.6 (0.5)

 EQ-5D-3L Self-Care Item

1.3 (0.5)

0.2 (0.5)

 FPIi Body Care domain

2.6 (0.6)

n/a

 FPIi Maintain Household

1.9 (0.9)

n/a

 FPIi Physical Exercise

1.6 (0.9)

n/a

Healthcare utilization, % of patients utilizing

 Oxygen therapy

18.4

14.9

 X-ray

53.1

52.3

 MRIj

21.6

28.9

 CTk

27.7

34.0

  1. aALTOS Acute Respiratory Distress Syndrome (ARDS) Network Long-term Outcomes Study (evaluated patients at 6- and 12-month time points); bICAP Improving Care of Acute Lung Injury (ALI) Patients; cMean (standard deviation); dIES-R Impact of Event Scale—Revised. eIES-6 Impact of Events Scale-6. fConstruct validity measures include mean values (SD) from visits at all available follow-up time points. gSF-36 Short Form Healthy Survey-36 Version 2. hHADS Hospital Anxiety and Depression Scale; iFPI Functional Performance Inventory collected for ALTOS only; jMRI magnetic resonance imaging; kCT computed tomography