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Table 1 Baseline characteristics of the propensity score-matched patients and healthy controls

From: The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT

 

Fungal infection (n = 82)

Bacterial infection (n = 80)

No infection (n = 77)

Healthy controls (n = 59)

p value

Age, median (IQR)

65 (54–75)

62 (48–72)

62 (52–73)

68 (60–75)

0.11

Gender, male (n, %)

58 (70.7%)

47 (58.8%)

47 (61.0%)

36 (61.0%)

0.40

BMI, median (IQR)

25.1 (22.7–28.4)

26.2 (23.1–29.4)

24.9 (22.5–28.4)

25.7 (23.0–28.0)

0.43

Malignancy (n, %)

25 (30.5%)

19 (23.8%)

19 (24.7%)

21 (35.6%)

0.39

Cirrhosis CP B/C (n, %)

10 (12.2%)

11 (13.8%)

8 (10.4%)

 

0.81

Diabetes mellitus (n, %)

12 (14.6%)

16 (20.0%)

8 (10.4%)

 

0.24

APACHE-II, median (IQR)

38 (31–42)

37 (31–40)

35 (31–40)

 

0.24

Sepsis at adm (n, %)

67 (81.7%)

65 (81.3%)

64 (83.1%)

 

0.95

Urgent admission (n, %)

77 (93.9%)

78 (97.5%)

73 (94.8%)

 

0.53

Diagnostic group (n, %)

    

0.09

 Cardiac surgery

5 (6.1%)

7 (8.8%)

3 (3.9%)

  

 Complicated surgery

47 (57.3%)

43 (53.8%)

41 (53.3%)

  

 Trauma/burns

4 (4.9%)

10 (12.5%)

2 (2.6%)

  

 Medical disease

26 (31.7%)

20 (25.0%)

31 (40.3%)

  

Steroids at adm (n, %)

28 (34.2%)

27 (33.8%)

27 (35.1%)

 

0.98

MV at adm (n, %)

69 (84.2%)

68 (85.0%)

61 (79.2%)

 

0.59

Randomisation Late-PN (n, %)

37 (45.1%)

39 (48.8%)

42 (54.6%)

 

0.49

Matching day, median (IQR)

6 (3–14)

8 (5–13)

7 (4–11)

 

0.10

  1. Matching day refers to the day of antimicrobial initiation for patients with a new infection and matched ICU day for patients without a new infection. Statistical analyses have been performed with the Kruskal-Wallis test for continuous variables and with the chi-square test for categorical variables
  2. IQR interquartile range, BMI body mass index, CP Child-Pugh, APACHE-II acute physiology and chronic health evaluation II, adm admission, MV mechanical ventilation, PN parenteral nutrition