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Table 1 Baseline characteristics

From: Vitamin A deficiency in critically ill children with sepsis

 

Sepsis group

Control group

P values

N = 160

N = 49

Age, months

12.00 (3.00, 49.75)

11.00 (4.00, 62.00)

0.782a

Age, n (%)

0.460b

 < 1 year

77 (48.1%)

26 (53.1%)

 

 1 year≤, < 5 years

47 (29.4%)

10 (20.4%)

 

 5 years≤

36 (22.5%)

13 (26.5%)

 

Gender

0.294b

 Male, n (%)

91 (56.9%)

32 (65.3%)

 

Race, n (%)

0.299c

 Tibetan

15 (9.4%)

3 (6.1%)

 

 Han

132 (82.5%)

45 (91.8%)

 

 Other

13 (8.1%)

1 (2.0%)

 

Weight, kg

7.75 (4.00, 14.86)

9.00 (5.75, 16.75)

0.216a

Setting, n (%)

0.652b

 Rural

79 (49.4%)

26 (53.1%)

 

 City

81 (50.6%)

23 (46.9%)

 

Mean VA status, mg/L

 Total

0.192 (0.106)

0.339 (0.119)

0.000d#

 < 1 year

0.192 (0.1043)

0.305 (0.131)

0.000d

 1 year≤, < 5 years

0.189 (0.095)

0.401 (0.093)

0.000d

 5 years≤

0.198 (0.125)

0.361 (0.091)

0.000d

VAD, n (%)

94 (58.8%)

6 (12.2%)

0.000b

 < 1 year

45 (47.9%)

6 (100.0%)

 

 1 year≤, < 5 years

27 (28.7%)

0

 

 5 years≤

22 (23.4%)

0

 

Source of infection, n (%)

 Respiratory system

40 (25.0%)

  

 Gastrointestinal system

73 (45.6%)

  

 Central nervous system

1 (0.6%)

  

 Blood stream

8 (5.0%)

  

 Soft tissue

10 (6.3%)

  

 Other

20 (12.5%)

  

 Respiratory and gastrointestinal system

5 (3.1%)

  

 Respiratory and central nervous system

2 (1.3%)

  

Severe sepsis, n (%)

29 (18.1%)

  

Septic shock, n (%)

25 (15.6%)

  

Length of stay, days

 PICU

6.70 (3.50, 12.87)

  

 Hospital

14.65 (8.93, 22.80)

  

PRISM

11.00 (7.00, 17.00)

  

Mortality, n (%)

 Hospital

7 (4.4%)

  

 28-day

11 (6.9%)

  

Time of ventilation, hours

24.00 (7.25, 117.50)

  

Positive blood culture, n (%)

14 (8.75%)

  
  1. Data are presented as means (SD), median (quartile 1, quartile 3) or number (percentage)
  2. VA vitamin A, VAD vitamin A deficiency, PICU pediatric intensive care unit, PRISM Pediatric Risk of Mortality score
  3. aMann-Whitney U test
  4. bChi-squared test
  5. cFisher exact test
  6. dStudent’s t test
  7. #P < 0.0001