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Fig. 1 | Critical Care

Fig. 1

From: Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis

Fig. 1

Endothelial glycocalyx dimensions measured in vivo and in vitro. a Boxplots of PBR values of healthy controls (white) and septic patients (grey) based on the different microvascular diameter ranges. b Correlation of sublingually measured PBR and paired syndecan-1 values. c A subpopulation from a was randomly selected, and ECs were incubated with 5% sterile-filtered human serum from three septic patients (black circles) and three apparently healthy individuals (white circles), respectively. Scatter plot showing the association between AFM-derived eGC decline (in vitro) and corresponding PBR values (in vivo). Each circle represents the mean of three independent experiments (consisting of ≥ 5 indentation curves in each of ≥ 10 cells) for each individual serum. Incubation without human serum served as control. Data are presented as mean ± SEM. AFM, atomic force microscopy; eGC, endothelial glycocalyx; ICU, intensive care unit; PBR, perfused boundary region; SEM, standard error of mean

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