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Table 2 Baseline characteristics of the study population according to the recovery of acute kidney injury

From: Recovery from acute kidney injury as a potent predictor of survival and good neurological outcome at discharge after out-of-hospital cardiac arrest

Variable

All patients with AKI (n = 175)

AKI non-recovery group (n = 106)

AKI recovery group (n = 69)

P value

Characteristics of AKI

 AKI stage (initial)

   

< 0.001

  Stage 1

120/175 (69)

57/106 (54)

63/69 (91)

 

  Stage 2

25/175 (14)

20/106 (19)

5/69 (7)

 

  Stage 3

30/175 (17)

29/106 (27)

1/69 (2)

 

 AKI stage (highest)

   

< 0.001

  Stage 1

68/175 (39)

16/106 (15)

52/69 (75)

 

  Stage 2

30/175 (17)

20/106 (19)

10/69 (15)

 

  Stage 3

77/175 (44)

70/106 (66)

7/69 (10)

 

Duration of AKI ≥ 4 days

88/175 (50)

66/106 (62)

22/69 (32)

< 0.001

 RRT frequency

45/175 (26)

41/106 (39)

4/69 (6)

< 0.001

 RRT duration ≥ 4 days

23/45 (51)

22/41 (54)

1/4 (25)

0.346

 †RRT requirements at discharge

4/8 (50)

4/6 (67)

0/2 (0)

0.429

Demographics

 Male sex

117/175 (67)

70/106 (66)

47/69 (68)

0.775

 Age ≥ 60 years

99/175 (57)

68/106 (64)

31/69 (45)

0.012

 Weight ≥ 60 kg

115/174 (66)

71/105 (68)

44/69 (64)

0.600

Medical history

 Heart failure

7/172 (4)

6/104 (6)

1/68 (2)

0.247

 Hypertension

84/173 (49)

56/105 (53)

28/68 (41)

0.118

 Diabetes mellitus

50/173 (29)

37/105 (35)

13/68 (19)

0.022

 Chronic kidney disease

10/172 (6)

9/104 (9)

1/68 (2)

0.091

Resuscitation

 Arrest cause

   

0.520

  Medical or uncertain

141/175 (81)

88/106 (83)

53/69 (77)

 

  Trauma

4/175 (2)

2/106 (2)

2/69 (3)

 

  Poisoning

2/175 (1)

0/106 (0)

2/69 (3)

 

  Drowning

0/175 (0)

0/106 (0)

0/69 (0)

 

  Asphyxia

28/175 (16)

16/106 (15)

12/69 (17)

 

 Arrest location

   

0.680

  Home

87/175 (50)

57/106 (54)

30/69 (44)

 

  Workplace

7/175 (4)

1/106 (1)

6/69 (9)

 

  Sport

1/175 (1)

0/106 (0)

1/69 (1)

 

  Street

46/175 (26)

27/106 (26)

19/69 (28)

 

  Public building

32/175 (18)

19/106 (18)

13/69 (19)

 

  Nursing home

2/175 (1)

2/106 (2)

0/69 (0)

 

Witnessed arrest

127/175 (73)

76/106 (72)

51/69 (74)

0.748

Bystander CPR

103/175 (59)

61/106 (58)

42/69 (61)

0.662

CPR time ≥ 20 min

101/156 (65)

71/96 (74)

30/60 (50)

0.002

Shockable rhythm

37/169 (22)

19/101 (19)

18/68 (27)

0.238

Adrenaline dose ≥ 4 mg

50/154 (33)

40/96 (42)

10/58 (17)

0.002

Post-resuscitation

 Shock

142/175 (81)

96/106 (91)

46/69 (67)

< 0.001

 Coronary angiography

30/175 (17)

13/106 (12)

17/69 (25)

0.034

 Target temperature = 33 °C

128/175 (73)

76/106 (72)

52/69 (75)

0.593

 TTM duration = 24 h

140/175 (80)

83/106 (78)

57/69 (83)

0.486

Outcomes

 Survival discharge

62/175 (35)

17/106 (16)

45/69 (65)

< 0.001

 MRS score 0 to 3 at discharge

25/175 (14)

3/106 (3)

22/69 (32)

< 0.001

  1. P < 0.05 are presented in italics
  2. †Thirty-seven patients receiving renal replacement therapy (RRT) died before discharge. Therefore, whether or not RRT was required could only be assessed in eight patients
  3. AKI acute kidney injury, RRT renal replacement therapy, CPR cardiopulmonary resuscitation, TTM targeted temperature management, MRS modified Rankin Scale