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Table 4 In the Beth Israel Deaconess Medical Center/St. Vincent’s cohort (100 patients), the 24-h increase in circulating heparan sulfate (an index of ongoing glycocalyx degradation) is independently associated with the volume of fluid resuscitation received over those 24 h

From: Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Change in plasma heparan sulfate (from time of study entry to 24 hours after enrollment)

Variable

Parameter estimate

Standard error

p

Intercept

-340.19

276.91

0.22

SOFA

-13.44

23.15

0.56

Age

6.50

4.26

0.13

Cumulative intravenous fluids, 0-24h

0.08

0.03

0.02