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Table 4 In the Beth Israel Deaconess Medical Center/St. Vincent’s cohort (100 patients), the 24-h increase in circulating heparan sulfate (an index of ongoing glycocalyx degradation) is independently associated with the volume of fluid resuscitation received over those 24 h

From: Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Change in plasma heparan sulfate (from time of study entry to 24 hours after enrollment)
Variable Parameter estimate Standard error p
Intercept -340.19 276.91 0.22
SOFA -13.44 23.15 0.56
Age 6.50 4.26 0.13
Cumulative intravenous fluids, 0-24h 0.08 0.03 0.02