Fig. 3
From: Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Volume of intravenous fluids administered early in sepsis predicts degree of glycocalyx degradation. The total volume of intravenous fluids administered in the first 24 h after ED presentation predicted the change in plasma heparan sulfate levels from initial blood draw to 24 h blood draw. Model R2 = 0.149, fit lines are shown for patients experiencing sepsis, severe sepsis, and septic shock, adjusted for age and baseline SOFA score