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Table 3 Multivariable logistic regression in the traditional and low tidal volume subgroups

From: Interaction between low tidal volume ventilation strategy and severity of acute respiratory distress syndrome: a retrospective cohort study

Variables

Model 1

Subgroup with PaO2/FiO2 > 150 (n = 345)

Model 2

Subgroup with PaO2/FiO2 ≤ 150 (n = 491)

Adjusted odds ratio (95% CI)

p

Adjusted odds ratio (95% CI)

p

Low tidal volume

0.42 (0.24–0.72)

0.002

0.88 (0.60–1.31)

0.554

Immunosuppression

3.60 (1.38–9.40)

0.009

1.42 (0.75–2.67)

0.274

Leukemia

0.87 (0.14–5.19)

0.887

5.52 (1.23–24.8)

0.026

Respiratory rate

1.02 (1.00–1.05)

0.032

1.02 (1.00–1.04)

0.008

Platelet count (109/L)

0.99 (0.99–0.99)

0.011

0.99 (0.99–1.00)

0.106

Age (years)

1.05 (1.03–1.06)

< 0.001

1.04 (1.02–1.05)

< 0.001

Fluid balance

1.10 (1.04–1.16)

0.001

1.05 (1.00–1.10)

< 0.001

  1. Note: The p value for interaction item (PaO2/FiO2 * low tidal volume) was 0.033 in Additional file 1: Table S1. The VIF value were 2.91 and 2.82, and the p values of goodness of fit are 0.479 and 0.355 for model 1 and model 2, respectively
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