Table 2 Subgroup analysis for relative risk (RR) of intervention vs. control
Type of study | Number of studies | Combined RR (95% CI) | p value | I2** | p value for I2 |
|---|---|---|---|---|---|
Early goal-directed therapy | 3 | 0.985 (0.860, 1.127) | 0.824 | 0.0% | 0.686 |
Hemofiltration | 2 | 1.149 (0.840, 1.573) | 0.384 | 44.6% | 0.179 |
Immunomodulation | 18 | 0.996 (0.931, 1.066) | 0.917 | 32.5% | 0.090 |
Modulation of coagulation and inflammation | 6 | 1.113 (1.019, 1.216) | 0.018 | 0.07% | 0.600 |
Other interventions | 7 | 0.912 (0.751, 1.106)* | 0.531 | 80.3% | < 0.001 |
Plasmapheresis | 1 | 0.995 (0.702, 1.410) | 0.978 | ||
Vasoactive drugs | 4 | 0.916 (0.804, 1.044) | 0.189 | 0.0% | 0.447 |
Fluid resuscitation | 3 | 1.019 (0.897, 1.159) | 0.769 | 0.0% | 0.593 |