MRSA respiratory ICU infection (n = 25) | Linezolid (15) | Vancomycin (10) | p value |
---|---|---|---|
Respiratory infection | 0.76 | ||
Tracheobronchitis | 2 | 2 | |
HAP | 2 | 2 | |
VAP | 8 | 5 | |
Early onset VAP | 4 | 4 | |
Late onset VAP | 4 | 1 | |
Severe CAP | 3 | 1 | |
Type of sample | 0.24 | ||
BAL | 2 | 0 | |
BAS | 10 | 10 | |
ETA | 2 | 0 | |
Pleural fluid | 1 | 0 | |
Microbial diagnostic | |||
Log CFU/mL | 6.0[4.0–6.0] | 5.0[4.0–6.0] | 0.40 |
Polymicrobial respiratory infection | 7 | 3 | 0.69 |
Radiographic consolidation | 0.34 | ||
None | 2 | 0 | |
Monolateral | 2 | 3 | |
Bilateral | 11 | 7 | |
Severity scores | |||
APACHE II ICU at microbial diagnosis | 17.0[11.5–22.8] | 17.5[6.5–22.3] | 0.58 |
SOFA ICU at microbial diagnosis | 8.0[1.8–10.0] | 7.0[5.5–10.8] | 0.55 |