Table 1 Baseline clinical characteristics of the population
MRSA respiratory ICU infection (n = 25) | Linezolid (n = 15) | Vancomycin (n = 10) | p value |
|---|---|---|---|
Age (years) | 63.4[57.0–69.7] | 56.1[32.8–66.6] | 0.13 |
Male sex | 12 (80.0) | 7 (70.0) | 0.65 |
APACHE II ICU admission | 21.0[15.5–23.5] | 18.0[13.3–22.0] | 0.24 |
SOFA ICU admission | 7.0[3.0–9.5] | 7.5[4.8–12.3] | 0.29 |
Coexisting illness/comorbidities | |||
CLD | 8 (53.3) | 2 (22.2) | 0.21 |
COPD | 4 | 1 | |
Bronchiectasis | 1 | 0 | |
Asthma | 1 | 1 | |
Lung cancer | 3 | 0 | |
Diabetes | 4 (25.0) | 0 | 0.13 |
Substance use behavior | |||
Alcohol use disorder | 5 (33.3) | 0 | 0.06 |
Current smoker | 8 (53.3) | 2 (20.0) | 0.21 |
Previous systemic antibiotics | 10 (66.7) | 6 (60.0) | 1.0 |
Previous colonization | 6 (40.0) | 6 (60.0) | 0.43 |
Previous corticosteroids (inhaled) | 2 (13.3) | 1 (10.0) | 1.0 |