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Table 2 Patient characteristics at admission, outcomes, and hospitals’ characteristics

From: Health inequities in the diagnosis and outcome of sepsis in Argentina: a prospective cohort study

 

Public hospitals’ ICUs = 23

Private hospitals’ ICUs = 26

Missing values

p value

Number of patients

367 (45)

442 (55)

  

Patient characteristics

 Patient origin upon entry to study

  

23

0.20

  Community

192/354 (54)

239/432 (55)

  

  Hospital

113/354 (32)

138/432 (32)

  

  ICU

40/354 (11)

40/432 (9)

  

  Third-level institution

5/354 (1)

14/432 (3)

  

  Unknown

4/354 (1)

1/432 (0)

  

 APACHE II

20 ± 9

N = 323

18 ± 7

N = 419

67

< 0.01

 SOFA

8 [5–11]

N = 354

6 [4–9]

N = 433

22

< 0.01

 Lactate (mmol/L)

2 [2–4]

N = 315

2 [1–3]

N = 404

90

< 0.01

 Admission with septic shock

172/367 (47)

155/442 (35)

0

< 0.01

 Use of mechanical ventilation

257/367 (70)

211/440 (48)

2

< 0.01

 Requirement of a fluid bolus of 30 ml/kg

264/367 (72)

309/442 (70)

0

0.47

 Time to first antibiotic dose (hours)

2 [1–3]

N = 301

2 [1–3]

N = 398

10

0.47

 Antibiotic administration

  

110

0.31

  Inadequate

39 (13)

43 (11)

  

  Adequate

168 (56)

245 (62)

  

  Negative cultures (%)

94 (31)

110 (28)

  

 Infections by highly resistant microorganisms†

93/367 (26)

85/442 (19)

0

0.02

Patient outcomes

 Length of mechanical ventilation (days)

8 [4–15]

N = 338

8 [3–16]

N = 407

64

0.44

 Length of ICU stay (days)

10 [4–20]

N = 359

9 [4–18]

N = 430

20

0.20

 Length of hospital stay (days)

18 [9–37]

N = 337

19 [9–31]

N = 390

82

0.22

 28-day mortality

153/367 (42)

107/442 (24)

0

< 0.01

 Hospital mortality

172/367 (47)

131/442 (30)

0

< 0.01

  1. Data are presented as n (%), mean ± standard deviation, or mdn [0.25–0.75] percentiles, unless specified
  2. APACHE II Acute Physiologic And Chronic Health Evaluation score, SOFA Sequential Organ Failure Assessment
  3. †Highly resistant microorganisms include methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, Pseudomonas aeruginosa, Acinetobacter baumannii, and β-lactamase-producing Klebsiellae