Table 1 Patient demographics, clinical parameters, and relevant investigation results
Characteristic | Overall | No coronary artery disease | Significant coronary artery disease | p valve | ||
|---|---|---|---|---|---|---|
Demographics | Number (n, %) | 40 | 34 (85%) | 6 (15%) | – | |
Female (%) | 28 (70%) | 25 (74%) | 3 (50%) | 0.25 | ||
Age (years) | 59.8 (± 17) | 58.1 (± 17) | 69.4 (± 18) | 0.02 | ||
Past medical history | Hypertension (%) | 16 (40%) | 13 (38%) | 3 (50%) | 0.67 | |
Diabetes (%) | 9 (22%) | 4 (12%) | 5 (83%) | 0.001 | ||
Smoking (%) | 14 (35%) | 11 (32%) | 3 (50%) | 0.65 | ||
Family history (%) | 4 (10%) | 3 (9%) | 1 (17%) | 0.55 | ||
Clinical parameters | Blood pressure | Systolic (mmHg) | 117 (102–127) | 114 (101–128) | 122 (± 10) | 0.9 |
Diastolic (mmHg) | 64 (± 13) | 65 (± 14) | 60 (± 13) | 0.39 | ||
Mean (mmHg) | 79 (68–94) | 83 (± 16) | 80 (± 10) | 0.57 | ||
Sinus rhythm (n, %) | 38 (95%) | 32 (94%) | 6 (100%) | 1.0 | ||
Heart rate (beats per min) | 86 (18) | 87 (± 19) | 78 (± 8) | 0.07 | ||
Weight (kg) | 80.4 (± 24) | 79.9 (± 25) | 83.7 (± 18) | 0.7 | ||
GCS | 11 (3–15) | 11 (3–15) | 11 (5–15) | 0.5 | ||
Catecholamines required (n, %) | 17 (43%) | 16 (47%) | 1 (17%) | 0.2 | ||
Dose (μg/kg/min) | 15.1 (± 10) | 15.1 (± 10) | 15 | – | ||
Mechanical ventilation (n, %) | 21 (53%) | 18 (53%) | 3 (50%) | 1.0 | ||
PaO2 (mmHg) | 78 (68–89) | 75 (66–88) | 88 (± 20) | 0.5 | ||
Platelets (ng/dL) | 231 (± 102) | 230 (± 103) | 239 (± 106) | 0.9 | ||
Creatinine (ng/dL) | 91 (61–170) | 89 (61–171) | 122 (± 64) | 0.8 | ||
Bilirubin (ng/dL) | 6.5 (5–15) | 8 (5–15) | 5 (4.5–17) | 0.3 | ||
SOFA score | 7 (5) | 7 (5) | 6 (5) | 0.6 | ||
APACHE III | 73 (32) | 72 (34) | 82 (7) | 0.3 | ||
Investigations | ECG | ST elevation, n(%) | 5 (13%) | 5 (15%) | 0 | – |
T wave inversion or flattening, n(%) | 29 (73%) | 24 (71%) | 5 (83%) | 1.0 | ||
ST depression, n(%) | 6 (15%) | 4 (12%) | 2 (33%) | 0.21 | ||
Biomarkers | Troponin I (ng/mL) | 1987 (400–4384) | 1943 (357–4182) | 3016 (1255–8630) | 0.28 | |
Echo | LV end diastolic diameter (mm) | 49.0 (8) | 48.6 (8) | 50.7 (7) | 0.54 | |
LV ejection fraction (%) | 45.7 (15) | 46.1 (15) | 43.2 (16) | 0.69 | ||
Wall motion score index | 2.0 (1.4–2.4) | 2.0 (1.5–2.4) | 1.8 (0.5) | 0.95 | ||
Global longitudinal strain (%) | − 9.2 (5) | − 9 (− 11 to − 6) | − 7 (− 16 to − 7) | 0.9 | ||