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Table 1 Clinical and laboratory characteristics of subjects

From: New-onset QT prolongation is a novel predictor of mortality in critically ill patients

 

All

Normal QT (N = 406)

QT prolongation (N = 99)

p

Age (years)

63.7 ± 18.2

62.8 ± 18.5

67.4 ± 16.6

0.20

Male (%)

305 (60.4)

237 (58.4)

68 (68.7)

0.06

Heart rate (BPM)

85.2 ± 20.4

83.7 ± 20.8

91.3 ± 17.5

0.01

Positive cTNT (%)

52.5

46.5

76.8

< 0.001

LogNT-proBNP

2.3 ± 0.7

2.2 ± 0.7

2.6 ± 0.6

0.91

Na+ (mmol/L)

140.2 ± 5.7

140.0 ± 5.5

141.0 ± 6.5

0.15

K+ (mmol/L)

3.9 ± 0.6

3.9 ± 0.6

3.8 ± 0.7

0.10

Cl- (mmol/L)

104.7 ± 6.4

104.6 ± 6.0

105.5 ± 7.8

0.04

Ca2+ (mmol/L)

2.08 ± 0.21

2.10 ± 0.19

2.02 ± 0.25

0.001

FBG (mmol/L)

7.53 ± 3.28

7.36 ± 3.02

8.26 ± 4.15

0.02

eGFR (mL/min/1.73 m2)

86.7 ± 44.1

91.6 ± 42.9

66.3 ± 43.5

0.49

CKD grade#

1.95 ± 1.13

1.80 ± 1.01

2.56 ± 1.35

< 0.001

APACHE- II (points)

15.0 ± 8.4

14.2 ± 8.0

18.7 ± 9.2

0.006

TT3 (nmol/L)

0.92 ± 0.45

0.96 ± 0.48

0.73 ± 0.25

0.004

TT4 (nmol/L)

86.4 ± 30.1

88.7 ± 30.9

77.4 ± 24.8

0.19

FT3 (pmol/L)

3.44 ± 1.10

3.52 ± 1.18

3.15 ± 0.59

0.17

FT4 (pmol/L)

15.5 ± 4.8

15.5 ± 5.1

15.4 ± 3.6

0.67

TSH (IU/mL)

1.34 ± 1.35

1.34 ± 1.28

1.32 ± 1.61

0.06

#NTIS (%)

59.3

55.0

76.3

< 0.001

  1. BPM beats per minute, FBG fasting blood glucose, eGFR estimated glomerular filtration rate, CKD chronic kidney disease, APACHE II score Acute Physiology and Chronic Health Evaluation II score. TT3 total triiodothyronine, TT4 total thyroxine, FT3 free triiodothyronine, FT4 free thyroxine, TSH thyroid-stimulating-hormone, rT3 reverse triiodothyronine, NTIS nonthyroidal illness syndrome
  2. #NTIS: Euthyroid patients with fT3 decreased below the normal range (< 3.5 pmol/L) during critical illness