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Table 1 Clinical and laboratory characteristics of subjects

From: New-onset QT prolongation is a novel predictor of mortality in critically ill patients

  All Normal QT (N = 406) QT prolongation (N = 99) p
Age (years) 63.7 ± 18.2 62.8 ± 18.5 67.4 ± 16.6 0.20
Male (%) 305 (60.4) 237 (58.4) 68 (68.7) 0.06
Heart rate (BPM) 85.2 ± 20.4 83.7 ± 20.8 91.3 ± 17.5 0.01
Positive cTNT (%) 52.5 46.5 76.8 < 0.001
LogNT-proBNP 2.3 ± 0.7 2.2 ± 0.7 2.6 ± 0.6 0.91
Na+ (mmol/L) 140.2 ± 5.7 140.0 ± 5.5 141.0 ± 6.5 0.15
K+ (mmol/L) 3.9 ± 0.6 3.9 ± 0.6 3.8 ± 0.7 0.10
Cl- (mmol/L) 104.7 ± 6.4 104.6 ± 6.0 105.5 ± 7.8 0.04
Ca2+ (mmol/L) 2.08 ± 0.21 2.10 ± 0.19 2.02 ± 0.25 0.001
FBG (mmol/L) 7.53 ± 3.28 7.36 ± 3.02 8.26 ± 4.15 0.02
eGFR (mL/min/1.73 m2) 86.7 ± 44.1 91.6 ± 42.9 66.3 ± 43.5 0.49
CKD grade# 1.95 ± 1.13 1.80 ± 1.01 2.56 ± 1.35 < 0.001
APACHE- II (points) 15.0 ± 8.4 14.2 ± 8.0 18.7 ± 9.2 0.006
TT3 (nmol/L) 0.92 ± 0.45 0.96 ± 0.48 0.73 ± 0.25 0.004
TT4 (nmol/L) 86.4 ± 30.1 88.7 ± 30.9 77.4 ± 24.8 0.19
FT3 (pmol/L) 3.44 ± 1.10 3.52 ± 1.18 3.15 ± 0.59 0.17
FT4 (pmol/L) 15.5 ± 4.8 15.5 ± 5.1 15.4 ± 3.6 0.67
TSH (IU/mL) 1.34 ± 1.35 1.34 ± 1.28 1.32 ± 1.61 0.06
#NTIS (%) 59.3 55.0 76.3 < 0.001
  1. BPM beats per minute, FBG fasting blood glucose, eGFR estimated glomerular filtration rate, CKD chronic kidney disease, APACHE II score Acute Physiology and Chronic Health Evaluation II score. TT3 total triiodothyronine, TT4 total thyroxine, FT3 free triiodothyronine, FT4 free thyroxine, TSH thyroid-stimulating-hormone, rT3 reverse triiodothyronine, NTIS nonthyroidal illness syndrome
  2. #NTIS: Euthyroid patients with fT3 decreased below the normal range (< 3.5 pmol/L) during critical illness