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Table 3 Multivariable linear regression model for an association between 24-h NT-proBNP levels and hand grip strength at 6 and 12 months after sepsis*

From: Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors

EffectEstimateSEp value
6-month hand grip strength
 Intercept57.183.86< 0.0001
 NT-proBNP (lowest tertile as reference)  0.0015
  Middle tertile− 1.632.020.4222
  Highest tertile− 9.302.600.0006
 Sex (female)− 16.181.88< 0.0001
 Race (non-Caucasian)2.803.410.4138
 Charlson comorbidity index− 0.090.520.8588
 Age− 0.320.090.0003
 CCI− 3.812.290.0990
12-month hand grip strength
 Intercept56.875.21< 0.0001
 NT-proBNP (lowest tertile as reference)  0.0427
  Middle tertile−
  Highest tertile− 8.713.610.0177
 Sex (female)− 15.612.21< 0.0001
 Race (non-Caucasian)3.652.830.2010
 Charlson comorbidity index− 0.050.620.9380
 Age− 0.310.120.0146
  1. Inverse probability weighting based on concurrent Zubrod scores was used to account for missing follow-up data, as well as absence due to death; NT-proBNP levels: lowest tertile (29–711 ng/L), middle tertile (712–2378 ng/L), and highest tertile (2379–70,000 ng/L)
  2. SE standard error, NT-proBNP N-terminal pro-brain natriuretic peptide, CCI chronic critical illness, APACHE Acute Physiology and Chronic Health Evaluation
  3. Overall p value
  4. Rapid recovery (RAP) patients as a reference group