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Fig. 6 | Critical Care

Fig. 6

From: Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study

Fig. 6

M2 microglia/macrophage polarization in rat brain 7 days after reperfusion. Rrepresentative images of Arg1 (M2 marker; orange), Iba1 (microglia marker; green), and DAPI (blue) multiple staining at the inner boundary of the infarction 7 days after reperfusion (a); quantification of M2 phenotype (Arg1+ Iba1+) (b) and microglia/macrophages (Iba1+) (c) at the inner boundary of the infarction. Significance was indicated with ****p < 0.0001. Treatment of argon significantly promoted the M2 microglia/macrophage polarization (p = 0.000095) in rat CNS 7 days after reperfusion. Results were represented as mean ± SD, n = 8 for tMCAO Ar group and n = 7 for tMCAO N2 group

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