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Fig. 4 | Critical Care

Fig. 4

From: Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study

Fig. 4

Neuronal nuclear antigen (NeuN) staining (ac) and Luxol Fast Blue myelin staining (d, e) of rat brain samples 7 days after reperfusion. Representative images of NeuN immunohistochemistry in cortex and subcortex of ischemic boundary zone (IBZ) 7 days after reperfusion (a); relative number of NeuN positive cells detected in cortex (b) and subcortex (c) of IBZ; relative positive area of white matter in external capsule (d) and striatum (e). Significance was indicated with ***p < 0.001, **p < 0.01, and *p < 0.05. Argon treatment significantly increased the relative numbers of NeuN-positive cells in cortex and subcortex of IBZ (p = 0.010 for cortex and p = 0.011 for subcortex). Results were represented as mean ± SD, n = 8 for tMCAO Ar group, n = 7 for tMCAO N2 group, n = 3 for sham Ar and sham N2 groups

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