From: Dysbiosis of the intestinal microbiota in neurocritically ill patients and the risk for death
Parameters | Univariate | Multivariate | ||
---|---|---|---|---|
HR (95%CI) | p value | aHR (95%CI) | p value | |
Candidate variables | ||||
 APACHE-II | 1.299 (1.008–1.674) | 0.044 |  |  |
 Respiratory failure | 3.853 (1.033–14.366) | 0.045 |  |  |
 Intracranial hypertension | 4.472 (1.115–17.938) | 0.035 |  |  |
 Serum lactate | 1.367 (1.042–1.793) | 0.024 |  |  |
The changes of the specific taxon abundance during first week after admission (z-score) | ||||
 ΔFusobacteria | 0.262 (0.097–0.708) | 0.008 | – | NS |
 ΔFusobacteriales | 0.262 (0.097–0.708) | 0.008 | – | NS |
 ΔEnterobacteriales | 1.756 (1.010–3.056) | 0.046 | 1.920♯ (1.016–3.628) | 0.044 |
 ΔVeillonellaceae | 1.475 (1.005–2.165) | 0.047 | – | NS |
 ΔFusobacteriaceae | 0.262 (0.097–0.706) | 0.008 | – | NS |
 ΔEnterobacteriaceae | 1.756 (1.010–3.056) | 0.046 | 1.920♯ (1.016–3.628) | 0.044 |