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Table 2 Cox regression analysis of risk factors associated with 180-day mortality in neurocritically ill patients (n = 98)

From: Dysbiosis of the intestinal microbiota in neurocritically ill patients and the risk for death

Parameters

Univariate

Multivariate

HR (95%CI)

p value

aHR (95%CI)

p value

Candidate variables

 Age

1.027 (1.004–1.051)

0.024

  

 APACHE-II

1.074 (1.005–1.146)

0.034

  

 WBC

1.091 (1.002–1.188)

0.045

  

 Cr

1.002 (1.000–1.004)

0.013

  

The abundance of specific taxa of the first sample (z-score)

 Christensenellaceae

1.429 (1.080–1.892)

0.013

1.545* (1.163–2.053)

0.003

 Erysipelotrichaceae

1.398 (1.029–1.900)

0.032

1.493* (1.094–2.038)

0.012

  1. *Adjusted for age, APACHE-II, white blood cell count and serum creatinine
  2. HR hazard ratio, aHR adjusted hazard ratio, 95%CI 95% confidence interval, SOFA Sequential Organ Failure Assessment, APACHE-II Acute Physiology and Chronic Health Evaluation-II, WBC white blood cell count, Cr creatinine