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Table 2 Cox regression analysis of risk factors associated with 180-day mortality in neurocritically ill patients (n = 98)

From: Dysbiosis of the intestinal microbiota in neurocritically ill patients and the risk for death

Parameters Univariate Multivariate
HR (95%CI) p value aHR (95%CI) p value
Candidate variables
 Age 1.027 (1.004–1.051) 0.024   
 APACHE-II 1.074 (1.005–1.146) 0.034   
 WBC 1.091 (1.002–1.188) 0.045   
 Cr 1.002 (1.000–1.004) 0.013   
The abundance of specific taxa of the first sample (z-score)
Christensenellaceae 1.429 (1.080–1.892) 0.013 1.545* (1.163–2.053) 0.003
Erysipelotrichaceae 1.398 (1.029–1.900) 0.032 1.493* (1.094–2.038) 0.012
  1. *Adjusted for age, APACHE-II, white blood cell count and serum creatinine
  2. HR hazard ratio, aHR adjusted hazard ratio, 95%CI 95% confidence interval, SOFA Sequential Organ Failure Assessment, APACHE-II Acute Physiology and Chronic Health Evaluation-II, WBC white blood cell count, Cr creatinine