Table 1 Characteristics of study participants
Characteristic | n (%) or median (IQR) |
|---|---|
Age (years) | 46 (40–51) |
Sex | |
Male | 7 (88%) |
Female | 1 (12%) |
Body mass index (kg/m2) | 22.6 (20.2–29.7) |
Weight (kg) | 68 (65–82) |
Serum creatinine (μmol/L) | 106 (78–197) |
Urinary creatinine clearance (mL/min) | 74 (53–109) |
Albumin (g/L) | 20 (18–24) |
Alanine transaminase (IU/mL) | 53 (28–60) |
Aspartate transaminase (IU/mL) | 47 (38–130) |
Alkaline phosphatase (IU/mL) | 75 (63–108) |
Total bilirubin (μmol/L) | 11 (10–20) |
APACHE II score (admission) | 17 (17–24) |
SOFA Score | |
Day 1 | 5 (3–6) |
Day 2 | 3 (2–4) |
Patients with positive culture | 4 (50%) |
Organisms isolated | |
Candida albicans | 2 (25%) |
Candida dubliniensis | 2 (25%) |
Candida parasilosis | 1 (12%) |
Candida glabrata complex | 1 (12%) |
Candida spp. | 1 (12%) |
Antifungals prescribed | |
Fluconazole | 6 (75%) |
Voriconazole | 2 (25%) |
Caspofungin | 3 (37%) |
Amphotericin | 1 (12%) |