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Table 1 Baseline characteristics

From: The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study

 

All patients

More than 48 h ICU stay

Patients and cultures baseline characteristics

Number of admissions between 1997 and 2017

 

17,511

9588

Age in years, mean (SD)

 

65.3 (14.5)

66.0 (13.6)

Males, N (%)/females N (%)

 

11,093 (63.4%)/6414 (36.6%)

6077 (63.4%)/3508 (36.3%)

Length of ICU stay in days, median (IQR)

 

3.0 (4.0)

6.0 (6.0)

APACHE II score

Median (IQR)

20.0 (11.0)

22.0 (11.0)

APACHE II < 20, N (%)

8281 (47.3%)

3428 (35.8%)

APACHE II > = 20, N (%)

8320 (47.5%)

5767 (60.1%)

Missing, N (%)

910 (5.6%)

393 (4.1%)

Patient category

Cardiothoracic surgery, N (%)

6109 (34.9%)

3021 (31.5%)

Internal medicine, N (%)

2434 (13.9%)

1666 (17.4%)

Surgery, N (%)

3361 (19.2%)

1751 (18.2%)

Cardiology, N (%)

2468 (14.1%)

1540 (16.1%)

Pulmonology, N (%)

1529 (8.7%)

1047 (10.9%)

Neurology, N (%)

527 (3.0%)

299 (3.1%)

Other, N (%)

1009 (5.8%)

264 (2.8%)

Missing, N (%)

74 (0.4%)

3 (0.03%)

Admission type

Medical*, N (%)

9335 (53.3%)

5787 (60.4%)

Elective surgery, N (%)

3964 (22.6%)

1696 (17.7%)

Scheduled surgery, N (%)

1264 (7.2%)

532 (5.5%)

Urgent surgery, N (%)

1553 (8.9%)

825 (8.6%)

Emergency surgery, N (%)

624 (3.6%)

358 (3.7%)

Missing, N (%)

771 (4.4%)

390 (4.1%)

Treated with SDD#

Yes, N (%)

12,054 (86.0%)

7141 (93.5%)

No, N (%)

1043 (7.4%)

83 (1.1%)

Missing, N (%)

919 (6.6%)

416 (5.4%)

ICU mortality, N (%)

 

2459 (14.0%)

1537 (16.0%)

Cultures

Distribution of specimen

Digestive tract cultures, N (%)

68,057 (41.9%)

 

Sputum cultures, N (%)

37,827 (23.3%)

 

Skin and wound cultures

7308 (4.5%)

 

Urine cultures

8212 (5.1%)

 

Blood cultures

27,884 (17.2%)

 

Abdominal cavity cultures

1125 (0.7%)

 

Other

11,236 (6.9%)

 

Unknown

586 (0.4%)

 

Total number of cultures

162,235

 
  1. Continuous data are shown as mean and standard deviation (SD) in case of normal distribution
  2. *Medical patients are all patients without previous surgery preceding ICU admission
  3. #Data available since 2002