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Table 4 ICU mortality by early change in daily SOFA scores

From: Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients

Change in SOFA scores1

Number of patients

ICU mortality, n (%)

Increase in SOFA score

No increase in SOFA score

p value4

Day 1 to day 2

15,736

764 (24.9)

1571 (12.4)

< 0.001

Day 1 to day 3

12,650

669 (27.1)

1134 (11.1)

< 0.001

Day 1 to day 4

10,206

538 (29.1)

943 (11.3)

< 0.001

Day 1 to day 5

8326

457 (31.6)

768 (11.2)

< 0.001

Day 2 to day 3

12,648

661 (21.7)

1141 (11.9)

< 0.001

Day 2 to day 4

10,203

590 (25.4)

890 (11.3)

< 0.001

Day 2 to day 5

8324

500 (28.5)

724 (11.0)

< 0.001

Day 3 to day 4

10,205

526 (22.1)

955 (12.2)

< 0.001

Day 3 to day 5

8326

450 (24.2)

775 (12.0)

< 0.001

Day 4 to day 5

8326

425 (21.4)

800 (12.6)

< 0.001

Day 1 to any day during ICU stay (any increase)

15,740

1382 (25.7)

954 (9.2)

< 0.001

Day 1 to any day during ICU stay (≥ 2 point increase)2

15,740

1124 (32.1)

1212 (9.9)

< 0.001

Day 1 to any day during ICU stay (≥ 3 point increase)3

15,740

903 (39.5)

1433 (10.7)

< 0.001

  1. SOFA Sequential Organ Failure Assessment
  2. 1Based on patients who had SOFA scores on both days
  3. 2Comparison is patients with an increase in SOFA score ≥ 2 vs. patients with an increase < 2 points or a decrease
  4. 3Comparison is patients with an increase in SOFA score ≥ 3 vs. patients with an increase < 3 points or a decrease
  5. 4p value is based on a chi-squared test
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