Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients

Table 2 Change in daily SOFA score for hospital survivors and non-survivors overall and by subgroups

		Mean rate of change in SOFA score per day (95% CI)
		Hospital survivors		Hospital non-survivors
		Days 1–7	Days 8–14	Days 1–7	Days 8–14
	Overall	− 0.55 (− 0.56, − 0.54) p < 0.001	− 0.13 (− 0.15, − 0.11) p < 0.001	− 0.25 (− 0.27, − 0.22) p < 0.001	− 0.01 (− 0.05, 0.03) p = 0.64
Admission SOFA score	≤ 11	− 0.47 (− 0.48, − 0.46) p < 0.001	− 0.09 (− 0.12, − 0.07) p < 0.001	− 0.13 (− 0.16, − 0.10) p < 0.001	− 0.004 (− 0.05, 0.04) p = 0.87
Admission SOFA score	> 11	−1.02 (− 1.06, − 0.98) p < 0.001	− 0.20 (− 0.26, − 0.15) p < 0.001	− 0.52 (− 0.57, − 0.47) p < 0.001	− 0.02 (− 0.11, 0.06) p = 0.58
Admission period	2004–2008	− 0.52 (− 0.54, − 0.50) p < 0.001	− 0.12 (− 0.15, − 0.09) p < 0.001	− 0.21 (− 0.25, − 0.17) p < 0.001	0.01 (− 0.05, 0.07) p = 0.78
Admission period	2009–2013	− 0.57 (− 0.59, − 0.55) p < 0.001	− 0.14 (− 0.17, − 0.11) p < 0.001	− 0.28 (− 0.32, − 0.24) p < 0.001	− 0.03 (− 0.09, 0.03) p = 0.37
ICU length of stay (days)	< 3	− 1.05 (− 1.11, − 1.00) p < 0.001	N/A	− 1.34 (− 1.53, − 1.15) p < 0.001	N/A
	3 to < 7	− 0.86 (− 0.89, − 0.84) p < 0.001	N/A	− 0.41 (− 0.48, − 0.35) p < 0.001	N/A
	≥ 7	− 0.48 (− 0.49, − 0.46) p < 0.001	−0.19 (− 0.21, − 0.17) p < 0.001	− 0.20 (− 0.23, − 0.17) p < 0.001	− 0.04 (− 0.09, 0.00) p = 0.04

SOFA Sequential Organ Failure Assessment, CI confidence interval, N/A Not applicable

ISSN: 1364-8535