From: Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study
Variables | T0 (baseline) | T10 | T20 | T30 | |
---|---|---|---|---|---|
MAP (mmHg) | NR | 73 ± 9.9 | 77.7 ± 11.3 | 76.5 ± 11.1 | 76 ± 11.7 |
PR | 75 ± 15.2 | 81.7 ± 15.6 | 82.6 ± 14.8 | 80.8 ± 14.6 | |
TR | 73.1 ± 10.7 | 81.4 ± 13.2 | 76.7 ± 14.4 | 75.9 ± 12.6 | |
SAP (mmHg) | NR | 114.7 ± 19.5 | 123.8 ± 22.2 | 122.4 ± 21.5 | 120.3 ± 21.7 |
PR | 112.2 ± 22.8 | 126.2 ± 22.4 | 125 ± 21.4 | 121.3 ± 22 | |
TR | 111.9 ± 18.5 | 127.3 ± 21.6 | 120.4 ± 21.3 | 118.9 ± 20.8 | |
DAP (mmHg) | NR | 54.6 ± 8.9 | 57.3 ± 9.8 | 56.4 ± 9.8 | 56.1 ± 9.8 |
PR | 59.4 ± 13 | 62.1 ± 12.2 | 61.6 ± 13.1 | 60.7 ± 12.2 | |
TR | 55.2 ± 8.8 | 59 ± 10.7 | 56.6 ± 11.5 | 56.5 ± 10.7 | |
HR (bpm) | NR | 93.5 ± 22.1 | 91.3 ± 21.4 | 90.3 ± 22.8 | 91.7 ± 21.9 |
PR | 92 ± 25.9 | 90.8 ± 23.5 | 91.7 ± 24.6 | 91.8 ± 24.6 | |
TR | 96.4 ± 24.3 | 93.3 ± 22.3 | 93.6 ± 23.1 | 94.5 ± 23.6 | |
EtCO2 (mmHg) | NR | 32.2 ± 6.2 | 31.7 ± 5.6 | 31.6 ± 5.7 | 31.7 ± 5.8 |
PR | 29.9 ± 5.6 | 29.8 ± 5.4 | 30.3 ± 5.6 | 29.9 ± 5.4 | |
TR | 31 ± 6.6 | 31.9 ± 6.6 | 32.1 ± 7 | 32 ± 7.4 | |
VTI (cm) | NR | 18.2 ± 5.3 | 19 ± 5.8 | 18.8 ± 5.9 | 18.6 ± 5.9 |
PR | 14.3 ± 3.6 | 19.5 ± 4.9 | 18.6 ± 5.2 | 18.9 ± 5.3 | |
TR | 16.2 ± 4.9 | 20.4 ± 5.5 | 18.1 ± 5.4 | 17.3 ± 5.4 | |
E wave (m s−1) | NR | 0.7 ± 0.2 | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 |
PR | 0.6 ± 0.2 | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.7 ± 0.2 | |
TR | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.7 ± 0.2 | |
A wave (m s−1) | NR | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 |
PR | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | |
TR | 0.7 ± 0.3 | 0.8 ± 0.3 | 0.8 ± 0.2 | 0.8 ± 0.3 | |
E/A ratio | NR | 1.1 ± 0.4 | 1.2 ± 0.4 | 1.1 ± 0.4 | 1.1 ± 0.4 |
PR | 0.9 ± 0.4 | 1 ± 0.4 | 1 ± 0.5 | 1 ± 0.5 | |
TR | 1.1 ± 0.8 | 1.2 ± 1.2 | 1 ± 0.3 | 0.9 ± 0.3 | |
E′ wave (m s−1) | NR | 0.1 ± 0.1 | 0.2 ± 0.2 | 0.2 ± 0.3 | 0.1 ± 0.2 |
PR | 0.2 ± 0.3 | 0.3 ± 0.4 | 0.3 ± 0.4 | 0.2 ± 0.4 | |
TR | 0.2 ± 0.2 | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.1 ± 0.2 | |
E/E′ ratio | NR | 7.9 ± 4 | 8 ± 4.2 | 7.8 ± 3.7 | 8.3 ± 3.9 |
PR | 5.7 ± 3.4 | 6.5 ± 3.6 | 6 ± 3.6 | 6.4 ± 3.4 | |
TR | 6.6 ± 3.2 | 8 ± 3 | 7.7 ± 3.3 | 7.4 ± 3.5 | |
ScVO2 (%) | NR | 74 ± 12.1 | 74.4 ± 11.7 | NA | 74 ± 12.1 |
PR | 76.1 ± 11.3 | 76.4 ± 8.2 | NA | 76.1 ± 11.3 | |
TR | 78.5 ± 8.5 | 79.1 ± 9.2 | NA | 78.5 ± 8.5 | |
Arterial lactate (mmol L−1) | NR | 2.7 ± 2.4 | 2.7 ± 2.8 | NA | 2.6 ± 2.8 |
PR | 3.4 ± 2.6 | 3.0 ± 2.0 | NA | 3.2 ± 2.1 | |
TR | 2.6 ± 2.1 | 2.3 ± 1.9 | NA | 2.5 ± 2.1 |