Table 2 Clinical outcomes
Outcome | Tube fastener (n = 153) | Adhesive tape (n = 145) | p value |
|---|---|---|---|
Primary outcome | |||
Lip ulcers, skin tear, tube dislodgement, or ventilator-associated pneumonia—no. of patients (%) | 12 (7.8) | 25 (17.2) | 0.014 |
Rate of primary outcome (per 1000 patient ventilator days) (95% CI) | 22.0 (16.3–27.7) | 52.6 (47.4–57.8) | 0.020 |
Components of primary outcome | |||
Lip ulcer—no. (%) | 4 (2.6) | 11 (7.3) | 0.050 |
Rate per 1000 patient ventilator days | 6.8 (5.6–8.0) | 19.3 (17.1–21.6) | 0.052 |
Skin tear—no. (%) | 2 (1.4) | 3 (2.1) | 0.610 |
Rate per 1000 patient ventilator days | 3.4 (2.0–4.8) | 5.3 (4.7–5.9) | 0.622 |
Tube dislodgement*—no. (%) | 6 (3.9) | 15 (10.3) | 0.030 |
Rate per 1000 patient ventilator days | 11.9 (6.5–17.3) | 28.1 (24.4–31.8) | 0.035 |
Secondary outcomes | |||
ETT repositioned—no. (%) | 17 (12.1) | 40 (29.0) | < 0.001 |
Self-extubations—no. (%) | 2 (1.3) | 2 (1.4) | 0.957 |
Ventilator-associated pneumonia | 0 (0) | 0 (0) | N/A |
MV duration (days) | 3.9 ± 3.0 | 3.9 ± 3.4 | 0.75 |
ICU mortality—no. (%) | 52 (34.0) | 51 (35.2) | 0.83 |
Hospital mortality—no. (%) | 57 (37.3) | 54 (37.2) | 0.99 |