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Table 1 Patient demographics

From: Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT)

Characteristics

Total (n = 148)

Ringer’s acetate (n = 75)

Ringer’s lactate (n = 73)

p value*

Sex, n (%)

 Male

112 (75.7)

56 (74.7)

56 (76.7)

0.772

 Female

36 (24.3)

19 (25.3)

17 (23.3)

 

Age [years], med (IQR)

67.5 (58.0–72.5)

66.0 (58.0–72.0)

68.0 (59.0–73.0)

0.631

ASA PS [class], n (%)

   

1.000

 3

3 (2.0)

2 (2.7)

1 (1.4)

 

 4

145 (98.0)

73 (97.3)

72 (98.6)

 

Euroscore, med (IQR)

18 (17–19)

18 (17–19)

18 (16–19)

0.542

SAPS, med (IQR)

54 (44–62)

54 (46–62)

54 (42–62)

0.945

NYHA [grade], n (%)

   

0.167

 0

11 (7.5)

5 (6.8)

6 (8.2)

 

 1

34 (23.1)

18 (24.3)

16 (21.9)

 

 2

69 (46.9)

34 (46.0)

35 (48.0)

 

 3

28 (19.1)

17 (23.0)

11 (15.1)

 

 4

5 (3.4)

0 (0.0)

5 (6.9)

 

Preoperative ejection fraction [%], med (IQR)

60 (55–65)

60 (55–65)

60 (55–65)

0.795

Preoperative eGFR [mL/min], med (IQR)

70 (53–85)

73 (51–87)

67 (54–83)

0.507

Type of surgery, n (%)

 Composite graft (+valve#)

20 (13.5)

4 (5.3)

16 (21.9)

0.004

 Other

128 (86.5)

71 (94.7)

57 (78.1)

 

  Single valve

107 (72.3)

59 (78.7)

48 (65.8)

 

  Single valve + CABG

12 (8.1)

5 (6.7)

7 (9.6

 

  Double valve

6 (4.1)

4 (5.3)

2 (2.7)

 

  Double valve + CABG

1 (0.7)

1 (1.3)

0 (0.0

 

  Triple valve

2 (1.4)

2 (2.7)

0 (0.0)

 

Duration anesthesia [min], med (IQR)

310 (266–362)

305 (266–353)

310 (264–364)

0.937

Duration surgery [min], med (IQR)

202 (170–251)

205 (176–251)

192 (170–264)

0.812

Aortic cross clamp time [min], med (IQR)

70 (56–90)

67 (53–86)

73 (58–97)

0.172

Hypothermic circulatory arrest n (%)

17 (11.56)

3 (4.00)

14 (19.18)

0.004

Red blood cell transfusions [mL]°, med (IQR)

340 (220–550)

333 (223–575)

350 (174–550)

0.788

Time until initial hemodynamic stabilization [h], med (IQR)

12.06 (9.7–13.9)

12.08 (10.0–13.4)

12.05 (9.1–14.1)

0.649

  1. *Wilcoxon rank sum test for continuous variables and chi-square test
  2. °Fisher’s exact test for categorical variables between the Ringer’s acetate and the Ringer’s lactate study groups including autologous retransfusion and red cell concentrates
  3. #One patient in the Ringer’s lactate group