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Table 1 Outcomes Assessed by MAP Response to Vasopressin or Angiotensin II

From: Broad spectrum vasopressors: a new approach to the initial management of septic shock?

  Vasopressin [14] Angiotensin II [6]
Responder 45% (n = 426) Non-responder 55% (n = 512) P value Responder 69.9% (n = 114) Non-responder 30.1% (n = 49) P value
In-patient mortality (%) 56.6% 71.7% < 0.001 35% 71% < 0.0001
Catecholamine dose (mcg/kg/min) 0.35 ± 0.25 0.33 ± 0.27 0.18 0.32 ± 0.32 0.53 ± 0.39 0.0002
MAP (mmHg) 69 ± 12 65 ± 12 < 0.001 67.1 ± 5.21 64.8 ± 5.02 0.0087
Steroids (%) 58.9 62.5 0.26 55.3 57.1 0.8647
Lactate (mmol/L) 4.0 ± 3.6 5.4 ± 4.8 < 0.001 3.43 ± 2.43 5.80 ± 6.01 0.013
SOFA score 13 ± 4 12 ± 3 0.49 11.65 ± 2.78 12.06 ± 2.99 0.4313
Age, years 62 ± 14 61 ± 15 0.17 61.7 ± 15.32 63.1 ± 16.33 0.4278