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Table 1 Outcomes Assessed by MAP Response to Vasopressin or Angiotensin II

From: Broad spectrum vasopressors: a new approach to the initial management of septic shock?

 

Vasopressin [14]

Angiotensin II [6]

Responder 45% (n = 426)

Non-responder 55% (n = 512)

P value

Responder 69.9% (n = 114)

Non-responder 30.1% (n = 49)

P value

In-patient mortality (%)

56.6%

71.7%

< 0.001

35%

71%

< 0.0001

Catecholamine dose (mcg/kg/min)

0.35 ± 0.25

0.33 ± 0.27

0.18

0.32 ± 0.32

0.53 ± 0.39

0.0002

MAP (mmHg)

69 ± 12

65 ± 12

< 0.001

67.1 ± 5.21

64.8 ± 5.02

0.0087

Steroids (%)

58.9

62.5

0.26

55.3

57.1

0.8647

Lactate (mmol/L)

4.0 ± 3.6

5.4 ± 4.8

< 0.001

3.43 ± 2.43

5.80 ± 6.01

0.013

SOFA score

13 ± 4

12 ± 3

0.49

11.65 ± 2.78

12.06 ± 2.99

0.4313

Age, years

62 ± 14

61 ± 15

0.17

61.7 ± 15.32

63.1 ± 16.33

0.4278