Skip to main content

Table 2 Least significant change of transthoracic echocardiography measurements between two examinations

From: What is the lowest change in cardiac output that transthoracic echocardiography can detect?

TTE parameters

Same operator

Different operator

LV parameters

E wave

8 [4–17]%

11 [5–19]%*

A wave£

9 [3–18]%

13 [6–23]%*

e’ wave

16 [7–34]%

19 [9–38]%

E/A ratio£

11 [6–19]%

11 [5–25]%

E/e’ ratio

24 [9–41]%

21 [10–39]%

s’ wave

14 [7–23]%

18 [8–27]%

 VTI

11 [5–18]%

14 [8–26]%*

 LVEF

8 [4–15]%

8 [3–19]%

RV parameters

 TAPSE

14 [6–27]%

17 [7–33]%

S wave

12 [6–24]%

15 [7–31]%*

LV and RV dimensions

 LVEDA

12 [7–21]%

15 [7–26]%

 RVEDA

15 [6–31]%

17 [10–33]%

 RVEDA/LVEDA ratio

17 [9–30]%

17 [7–35]%

  1. n = 100, data are summarised as median [interquartile range]
  2. LV left ventricular, RV right ventricular, TTE transthoracic echocardiography, E early peak velocity of transmitral flow with pulsed Doppler, A atrial peak velocity of transmitral flow with pulsed Doppler, e’ early diastolic peak velocity of the lateral mitral annulus with tissue Doppler imaging, s’ systolic peak velocity of the lateral mitral annulus with tissue Doppler imaging, VTI velocity-time integral of the left ventricular outflow tract, LVEF left ventricular ejection fraction, TAPSE tricuspid annular plane systolic excursion, S systolic peak velocity of the tricuspid annulus with tissue Doppler imaging, LVEDA left ventricular end-diastolic area, RVEDA right ventricular end-diastolic area
  3. *p < 0.05 different vs. same operator
  4. £Concerning the A wave and the E/A ratio, n = 84