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Fig. 2 | Critical Care

Fig. 2

From: Mechanical ventilation causes diaphragm dysfunction in newborn lambs

Fig. 2

Proteolysis pathways in mechanically ventilated newborn diaphragms. a Transcript levels of muscle-specific E3 ubiquitin ligases (Atrogin1, MuRF1) and SIRT1 in the diaphragm. b Transcript levels of autophagy genes LC3B and Gabarapl1, expressed as fold change relative to CTL values. c Representative immunoblot and group mean values for LC3B-I and LC3B-II protein in the diaphragm. *p < 0.05 versus CTL; #p < 0.05 for MV versus MV+SD

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