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Table 2 Characteristics of study population on admission and during the ICU stay. Data are presented as counts (percentage) or median [IQRs]

From: Death after awakening from post-anoxic coma: the “Best CPC” project

 

All (n = 196)

OHCA (n = 82)

IHCA (n = 114)

Male, n (%)

132 (67)

60 (72)

72 (63)

Age, years

73 [62–79]

73 [65–79]

73 [60–79]

Estimated weight, kg

75 [70–85]

75 [70–82]

76 [70–89]

Comorbidities

 Chronic hypertension

75 (38)

29 (35)

46 (40)

 Diabetes

60 (31)

24 (29)

36 (32)

 NYHA III–IV heart failure

27 (14)

6 (7)

21 (18) *

 Chronic coronary artery disease

86 (44)

32 (39)

54 (47)

 Previous vascular neurological disease

32 (16)

18 (22)

14 (12)

 Liver cirrhosis

17 (9)

4 (5)

13 (11)

 COPD/asthma

50 (26)

14 (17)

36 (32) *

 Chronic hemodialysis

30 (15)

7 (9)

23 (20) *

 Immunosuppression

10 (5)

4 (5)

6 (5)

CA characteristics

 Time of ROSC, min

12 [6–20]

17 [12–25]

10 [5–15] *

 Adrenaline, mg

2 [1–3]

3 [1–4]

1 [1–1] *

 Witnessed, n (%)

167 (85)

66 (80)

101 (89)

 Bystander CPR, n (%)

147 (75)

52 (63)

95 (83) *

 Cardiac cause, n (%)

152 (78)

60 (73)

92 (81)

 Non-shockable rhythm, n (%)

127 (65)

43 (52)

84 (74) *

 ECPR, n (%)

15 (8)

5 (6)

10 (9)

After hospital admission

 Lactate on admission, mmol/dL

5.4 [2.9–8.4]

5.7 [2.9–8.4]

5.2 [2.9–8.4]

 Vasopressor use, n (%)

178 (91)

74 (90)

104 (91)

 Dobutamine use, n (%)

107 (55)

44 (54)

63 (55)

 TTM, n (%)

117 (60)

66 (80)

51 (45) *

 Infection, n (%)

89 (45)

36 (44)

53 (46)

 Shock, n (%)

148 (76)

69 (84)

79 (69) *

 IABP, n (%)

16 (8)

6 (7)

10 (9)

 Post-ROSC ECMO, n (%)

13 (7)

3 (4)

10 (9)

 RRT, n (%)

71 (36)

17 (21)

54 (47) *

 MV, n (%)

195 (99)

82 (100)

113 (99)

 Bleeding, n (%)$

48 (24)

16 (20)

32 (28)

 ICU length of stay, days

8 [3–16]

9 [1–16]

7 [3–15]

  1. ECPR extracorporeal cardiopulmonary resuscitation, ECMO extra-corporeal membrane oxygenation, ICU intensive care unit, NYHA New York Heart Association, COPD chronic pulmonary obstructive disease, CA cardiac arrest, IABP intra-aortic balloon counterpulsation, TTM targeted temperature management, RRT renal replacement therapy, MV mechanical ventilation
  2. $Reduction of hemoglobin of at least 2 g/dL over 24 h requiring red blood cells transfusion
  3. *p < 0.05 between IHCA and OHCA