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Table 2 Characteristics of study population on admission and during the ICU stay. Data are presented as counts (percentage) or median [IQRs]

From: Death after awakening from post-anoxic coma: the “Best CPC” project

  All (n = 196) OHCA (n = 82) IHCA (n = 114)
Male, n (%) 132 (67) 60 (72) 72 (63)
Age, years 73 [62–79] 73 [65–79] 73 [60–79]
Estimated weight, kg 75 [70–85] 75 [70–82] 76 [70–89]
Comorbidities
 Chronic hypertension 75 (38) 29 (35) 46 (40)
 Diabetes 60 (31) 24 (29) 36 (32)
 NYHA III–IV heart failure 27 (14) 6 (7) 21 (18) *
 Chronic coronary artery disease 86 (44) 32 (39) 54 (47)
 Previous vascular neurological disease 32 (16) 18 (22) 14 (12)
 Liver cirrhosis 17 (9) 4 (5) 13 (11)
 COPD/asthma 50 (26) 14 (17) 36 (32) *
 Chronic hemodialysis 30 (15) 7 (9) 23 (20) *
 Immunosuppression 10 (5) 4 (5) 6 (5)
CA characteristics
 Time of ROSC, min 12 [6–20] 17 [12–25] 10 [5–15] *
 Adrenaline, mg 2 [1–3] 3 [1–4] 1 [1–1] *
 Witnessed, n (%) 167 (85) 66 (80) 101 (89)
 Bystander CPR, n (%) 147 (75) 52 (63) 95 (83) *
 Cardiac cause, n (%) 152 (78) 60 (73) 92 (81)
 Non-shockable rhythm, n (%) 127 (65) 43 (52) 84 (74) *
 ECPR, n (%) 15 (8) 5 (6) 10 (9)
After hospital admission
 Lactate on admission, mmol/dL 5.4 [2.9–8.4] 5.7 [2.9–8.4] 5.2 [2.9–8.4]
 Vasopressor use, n (%) 178 (91) 74 (90) 104 (91)
 Dobutamine use, n (%) 107 (55) 44 (54) 63 (55)
 TTM, n (%) 117 (60) 66 (80) 51 (45) *
 Infection, n (%) 89 (45) 36 (44) 53 (46)
 Shock, n (%) 148 (76) 69 (84) 79 (69) *
 IABP, n (%) 16 (8) 6 (7) 10 (9)
 Post-ROSC ECMO, n (%) 13 (7) 3 (4) 10 (9)
 RRT, n (%) 71 (36) 17 (21) 54 (47) *
 MV, n (%) 195 (99) 82 (100) 113 (99)
 Bleeding, n (%)$ 48 (24) 16 (20) 32 (28)
 ICU length of stay, days 8 [3–16] 9 [1–16] 7 [3–15]
  1. ECPR extracorporeal cardiopulmonary resuscitation, ECMO extra-corporeal membrane oxygenation, ICU intensive care unit, NYHA New York Heart Association, COPD chronic pulmonary obstructive disease, CA cardiac arrest, IABP intra-aortic balloon counterpulsation, TTM targeted temperature management, RRT renal replacement therapy, MV mechanical ventilation
  2. $Reduction of hemoglobin of at least 2 g/dL over 24 h requiring red blood cells transfusion
  3. *p < 0.05 between IHCA and OHCA