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Table 1 Test accuracy for prediction of hospitalisation avoidance by Saeed et al. and from our data

From: Application of MR-ProADM to predict prevention of hospitalisation, derived from a multi-centre study

 

Graziadio et al [2]

Saeed et al [1]

MR-proADM

Sensitivity

0.60 [0.44–0.71]

0.75 [0.72–0.78]

Specificity

0.60 [0.53–0.66]

0.80 [0.74–0.84]

LR+

1.24 [0.82–1.86]

3.69 [2.90–4.71]

LR−

0.78 [0.44–1.37]

0.31 [0.27–0.35]

PPV

0.19 [0.14–0.87]

0.93 [0.91–0.95]

NPV

0.87 [0.79–0.92]

0.48 [0.43–0.52]

CRP

Sensitivity

0.85 [0.62–0.97]

0.42 [0.39–0.45]

Specificity

0.21 [0.13–0.30]

0.77 [0.72–0.82]

LR+

1.07 [0.87–1.32]

1.84 [1.45–2.33]

LR−

0.72 [0.24–2.19]

0.75 [0.69–0.82]

PPV

0.18 [0.15–0.21]

0.87 [0.83–0.89]

NPV

0.88 [0.70–0.96]

0.27 [0.24–0.31]

  1. MR-proADM mid-regional pro-adrenomedullin, CRP C-reactive protein, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio