Fig. 5
Top regulated canonical pathways based on their z-score analyzed through Ingenuity Pathway Analysis. PO2 oscillations resulted in significantly altered levels of mRNAs enriched in canonical pathways predicting a changed activation status of several pathways. The calculated z-score indicates a pathway with genes exhibiting overall increased mRNA levels (blue bars) or decreased mRNA levels (orange bars). The ratio (orange dots connected by a line) indicates the ratio of genes from the dataset that map to the pathway divided by the total number of genes that map to the same pathway