Table 1 Baseline and peri-operative characteristics*
From: Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial
Control (N = 15) | CytoSorb (N = 15) | |
|---|---|---|
Pre-operative characteristics | ||
Median age—(IQR) years | 69 (49–80) | 67 (44–76) |
Male sex—no. (%) | 11 (73.3) | 13 (86.7) |
Median body weight—(IQR) kg | 80 (76–94) | 86 (73–91) |
Median left ventricular ejection fraction—(IQR) % | 60 (35–65) | 53 (43–57) |
Median Euroscore II—(IQR) % | 5.1 (2.1–7.2) | 3.0 (2.2–9.1) |
Coexisting conditions—no. (%) | ||
Chronic kidney disease† | 4 (26.7) | 3 (20) |
Chronic heart failure ‡ | 5 (33.3) | 2 (13.3) |
Hypertension± | 9 (60.0) | 10 (66.7) |
Diabetes± | 2 (13.3) | 4 (26.7) |
Cerebro-vascular disease∞ | 1 (6.7) | 0 (0) |
Peripheral vascular disease | 4 (26.7) | 3 (42.9) |
Smoking | 6 (40) | 7 (46.7) |
Chronic obstructive pulmonary disease£ | 2 (13.3) | 1 (6.7) |
Mean pre-op haemoglobin level—(SD) g/L | 134 (19) | 132 (19) |
Mean pre-op creatinine level—(SD) μmol/L | 104 (34) | 89 (22) |
Intraoperative characteristics | ||
Type of procedure—no. (%) | ||
CABG or single valve replacement | 2 (13.3) | 2 (13.3) |
Double valve replacement | 1 (6.7) | 0 (6.7) |
CABG and valve replacement | 6 (40) | 3 (20) |
Ascending aortic procedure | 5 (33.3) | 5 (33.3) |
Others | 1 (6.7) | 5 (33.3) |
Cardio-pulmonary bypass characteristics | ||
Median bypass duration—(IQR) min | 138 (87–207) | 145 (130–183) |
Median cross-clamp duration (IQR) min | 115 (68–159) | 122 (97–146) |
Centrifugal pump—no. (%) | 5 (33.3) | 4 (26.7) |
Ultrafiltration—no. (%) | 9 (45) | 11 (73.3) |
Median ultrafiltration volume—(IQR) mL | 1000 (0–2500) | 1500 (0–2000) |
Modified ultrafiltration—no. (%) | 2 (13.3) | 2 (13.3) |
Modified ultrafiltration volume—(IQR) mL | 0 (0–0) | 0 (0–0) |
Fluid Balance at T2—(IQR) mL | 2840 (2105–3643) | 3125 (2480–3946) |
Fluid Balance at T3—(IQR) mL | 4371 (2921–5181) | 4324 (3556–5460) |
Fluid Balance at T4—(IQR) mL | 6551 (5139–7301) | 6702 (5657–7332) |
Median SAPS II on ICU admission (IQR) | 37.0 (34.0–49.0) | 43.0 (21.0–48.0) |