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Table 1 Relationship between fluid balance and mortality—retrospective analysis of the VASST study. Adapted from Boyd et al. [7]

From: Sepsis: personalization v protocolization?

  Quartile 1 Quartile 2 Quartile 3 Quartile 4
12-h fluid balance 710 (− 132–1480) 2880 (2510–3300) 4900 (4290–5530) 8150 (7110–10,100)
4-day fluid balance 1560 (− 723–3210) 8120 (6210–9090) 13,000 (11,800–14,700) 20,500 (17,700–24,500)
Adjusted hazard ratio vs quartile 4
 - 12 h 0.57 (0.41–0.80) 0.58 (0.41–0.82) 0.76 (0.56–1.03)
 - 4 days 0.47 (0.30–0.72) 0.51(0.34–0.78) 0.74 (0.50–1.09)
  1. Volumes expressed as median (inter-quartile range)