Variable | Single variable | p value | Multivariable | p value |
---|---|---|---|---|
Age | 1.62 (1.36–1.93) | < 0.001 | 1.31 (1.07–1.61) | < 0.01 |
Sex (males are reference) | 0.94 (0.76–1.17) | 0.59 | 0.98 (0.76–1.25) | 0.86 |
APACHE III | 2.24 (1.90–2.64) | < 0.001 | 1.98 (1.62–2.40) | < 0.001 |
% Days with deep sedation | 4.70 (3.76–5.88) | < 0.001 | 5.42 (4.23–6.95) | < 0.001 |
% Days with agitation | 1.57 (0.32–7.71) | 0.58 | 39.9 (6.53–243) | < 0.001 |
Hospital site 1 (reference) | 1.00 | 1.00 | 1.00 | |
Hospital site 2 | 0.70 (0.52–0.96) | 0.03 | 0.63 (0.43–0.90) | 0.01 |
Hospital site 3 | 0.66 (0.47–0.93) | 0.02 | 0.79 (0.53–1.18) | 0.25 |
Hospital site 4 | 0.58 (0.43–0.78) | < 0.001 | 0.45 (0.32–0.62) | < 0.001 |
Hospital site 5 | 1.35 (0.89–2.06) | 0.16 | 0.93 (0.57–1.54) | 0.78 |