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Table 2 Sedation status associated with 90-day mortality

From: Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort

Variable

Single variable

p value

Multivariable

p value

Age

1.62 (1.36–1.93)

< 0.001

1.31 (1.07–1.61)

< 0.01

Sex (males are reference)

0.94 (0.76–1.17)

0.59

0.98 (0.76–1.25)

0.86

APACHE III

2.24 (1.90–2.64)

< 0.001

1.98 (1.62–2.40)

< 0.001

% Days with deep sedation

4.70 (3.76–5.88)

< 0.001

5.42 (4.23–6.95)

< 0.001

% Days with agitation

1.57 (0.32–7.71)

0.58

39.9 (6.53–243)

< 0.001

Hospital site 1 (reference)

1.00

1.00

1.00

 

Hospital site 2

0.70 (0.52–0.96)

0.03

0.63 (0.43–0.90)

0.01

Hospital site 3

0.66 (0.47–0.93)

0.02

0.79 (0.53–1.18)

0.25

Hospital site 4

0.58 (0.43–0.78)

< 0.001

0.45 (0.32–0.62)

< 0.001

Hospital site 5

1.35 (0.89–2.06)

0.16

0.93 (0.57–1.54)

0.78