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Table 1 Participant demographics and outcomes

From: Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort

Variable

Total participants (n = 1657)

Analytical sample (n = 1338)

Excluded sample (n = 319)

Included vs excluded p value

Demographics

 Male, % (n)

54.7 (907)

56.2 (753)

48.3 (154)

< 0.01

 Age in years, mean (SD)

60.0 (18.9)

58.9 (19.0)

64.8 (17.7)

< 0.01

Main outcomes

 MV-free days, mean (SD)

10.1 (10.7)

9.6 (10.4)

12.2 (11.7)

< 0.01

 ICU-free days, mean (SD)

7.3 (8.9)

6.7 (8.5)

9.9 (10.1)

< 0.01

 Hospital-free days, mean (SD)

11.1 (16.6)

10.8 (16.4)

12.4 (17.5)

<0.05

 90-day mortality, % (n)*

49.1 (810)

50.1 (669)

44.5 (141)

0.07

Clinical parameters

 APACHE II score, mean (SD)

24.0 (7.8)

24.1 (7.9)

23.6 (7.5)

0.22

 APACHE III score, mean (SD)

82.7 (28.1)

83.6 (28.3)

78.9 (26.9)

< 0.01

 SOFA score, mean (SD)

9.5 (3.5)

9.7 (3.5)

8.8 (3.6)

< 0.01

 Prevalence of ARDS, % (n)**

17.5 (289)

19.7 (262)

8.5 (27)

< 0.01

Hospital admission type***

0.56

 Medical, % (n)

72.3 (1196)

72.4 (968)

71.7 (228)

 

 Trauma, % (n)

10.7 (177)

11.6 (155)

6.9 (22)

 Surgical (scheduled), % (n)

3.5 (58)

3.1 (42)

5.0 (16)

 Surgical (unscheduled), % (n)

10.8 (178)

9.8 (131)

14.8 (47)

 Other, % (n)

2.8 (46)

3.1 (41)

1.6 (5)

  1. *From the 1657 participants, there were 6 participants whose death by 90 days was not recorded. Percentages (%) are obtained from all the participants whose status was known by 90 days
  2. **From the 1657 participants there were 8 participants whose ARDS diagnosis was not determined. Percentages are obtained based on all participants where a yes/no ARDS diagnosis was recorded.
  3. ***From the 1657 participants there were 2 participants whose admission type was not obtained. Percentages are obtained from all those participants whose admission was obtained