Table 3 Patient characteristics split into angiography within 6 h of CA or later/no angiography
Coronary angiography in the first 6 h (n = 516) | No coronary angiography in first 6 h (n = 319) | p value | |
|---|---|---|---|
Baseline variables | |||
Age (years) | 63 (56–70) | 69 (59–77) | < 0.0001 |
Sex (male) | 438/516 (85%) | 247/319 (77%) | 0.01 |
Hypertension | 220/514 (43%) | 118/319 (37%) | 0.11 |
CHF (NYHA 3–4) | 25/515 (5%) | 31/319 (10%) | 0.01 |
Any IHD, PCI, AMI, CABG | 149/516 (29%) | 118/319 (37%) | 0.02 |
Diabetes | 62/515 (12%) | 59/316 (19%) | 0.01 |
Cardiac arrest variables | |||
Shockable rhythm | 438/516 (84%) | 231/319 (73%) | < 0.0001 |
Bystander CPR | 393/516 (76%) | 223/319 (70%) | 0.05 |
Time CA-ROSC (min) | 25 (17–38) | 25 (16–40) | 0.85 |
Shock on admission | 67/516 (13%) | 44/319 (14%) | 0.75 |
Lactate on admission (mmol/L) | 5.1 (2.4–8.8) (n = 477) | 6.2 (3.6–9.5) (n = 310) | 0.001 |
ST-elevation on ECG | 279/513 (54%) | 57/315 (18%) | < 0.0001 |
PCI | 342/516 (66%) | 23/319 (7%) | < 0.0001 |
IABP | 107/515 (20%) | 25/319 (8%) | < 0.0001 |
TTM 33 °C | 254/516 (49%) | 157/319 (49%) | 1.00 |
Any vasoactive drug day 1 | 404/511 (79%) | 233/317 (74%) | 0.07 |
Day 2 | 438/510 (86%) | 252/316 (80%) | 0.03 |
Day 3 | 377/508 (74%) | 221/317 (70%) | 0.17 |
Noradrenaline or epinephrine > 0.1 μg/kg/min days 1–3 | 261/516 (50%) | 171/317 (54%) | 0.35 |
Renal variables/outcomes | |||
Baseline creatinine (μmol/L) | 100 (85–120) (n = 499) | 105 (85–130) (n = 312) | 0.04 |
Creatinine > 130 μmol/L | 78/499 (16%) | 68/312 (22%) | 0.03 |
Worst AKI stage first week | |||
Stage 1 | 86/516 (17%) | 51/319 (16%) | 0.85 |
Stage 2 | 59/516 (11%) | 55/319 (17%) | 0.02 |
Stage 3 | 71/516 (14%) | 55/319 (17%) | 0.20 |
Any AKI first week | 216/516 (42%) | 161/319 (50%) | 0.02 |
Daily fluid balance | |||
Day 2 | 1500 (500–2500) (n = 513) | 1600 (500–2700) (n = 318) | 0.64 |
Day 3 | 300 (− 500 to + 1400) (n = 504) | 500 (− 400 to + 1800) (n = 309) | 0.12 |
RRT during first week | 47/516 (9%) | 27/319 (9%) | 0.80 |
Survival at 6 months | 311/516 (60%) | 153/319 (48%) | 0.0006 |