Renal function after out-of-hospital cardiac arrest; the influence of temperature management and coronary angiography, a post hoc study of the target temperature management trial

Table 2 Results of logistic regression

	Significance	Odds ratio	95% CI
Coronary angiography < 6 h	0.09	0.73	0.50–1.05
Temperature (36 °C)	0.10	0,75	0.54–1.06
Age (per year)	0.18	1.01	0.99–1.03
Sex (female)	0.09	0.67	0.43–1.06
Diabetes	0.07	0.61	0.36–1.04
Hypertension	0.60	1.10	0.77–1.58
Heart failure	0.50	1.26	0.64–2.46
Creatinine on admission	0.02	1.01	1.00–1.01
Time to ROSC (per minute)	0.05	1.01	1.00–1.02
Bystander CPR	0.62	1.10	0.74–1.63
Shock	0.18	1.42	0.84–2.41
Shockable rhythm	0.04	0.63	0.40–0.98
Lactate clearance	0.20	0.77	0.52–1.14
No vasopressor, dobutamine or DA < 5 μg/kg/min	0.32
DA > 5 μg/kg/min or NE < 0.25 μg/kg/min	0.52	0.87	0.56–1.34
NE or Epi ≥ 0.25 μg/kg/min	0.30	1.34	0.77–2.35
NE or Epi ≥ 0.75 μg/kg/min	0.67	1.23	0.43–3.47
IABP	0.003	2.22	1.32–3.74
Maximum blood glucose within 24 h	0.24	1.02	0.98–1.06

Results of logistic regression, angiography within 6 h of cardiac arrest vs. no early angiography. Increasing time to ROSC, a higher serum creatinine on admission and treatment with IABP were independently associated with a higher risk of AKI whereas an initial shockable rhythm was associated with less AKI. Normal lactate clearance was defined as lactate < 2.0 mmol/L alt 12 h or a decrease in lactate > 50% within 12 h of cardiac arrest
Abbreviations: ROSC return of spontaneous circulation, CPR cardiopulmonary resuscitation, DA dopamine, NE norepinephrine, Epi epinephrine, IABP intra-aortic balloon pump

ISSN: 1364-8535