Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the ‘Protein & Energy Requirements Fed for Every Critically ill patient every Time’ (PERFECT) protocol: a before-and-after study

Table 4 Multiple regression analysis: showing analysis of morning BG, plus insulin and propofol requirement

Variable and adjustment	Morning blood glucose			Insulin prescription			Propofol
Variable and adjustment	B	p	95% CI	B	p	95% CI	B	p	95% CI
Group*	0.426	0.157	− 0.166 to 1.018	2.990	0.574	− 7.561 to 13.540	52.364	0.107	− 11.572 to 116.299
BMI	0.005	0.777	− 0.031 to 0.041	0.314	0.330	− 0.324 to 0.952	3.258	0.102	− 0.664 to 7.181
% Energy	0.011	0.316	− 0.010 to 0.032	0.203	0.272	− 0.162 to 0.568	1.197	0.294	− 1.058 to 3.451
APACHE-II	0.000	0.992	− 0.050 to 0.051	1.424	0.003	0.514 to 2.234	0.235	0.932	− 5.192 to 5.661
Diabetes⁺	1.051	0.001	0.456 to 1.646	40.088	< 0.001	29.013 to 51.163	–	–	–

B unstandardized regression coefficients, APACHE-II Acute Physiology and Chronic Health Evaluation II, BMI body mass index, CI confidence interval
*VBF versus RBF
⁺Having diabetes versus not

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