Table 1 General characteristics of patients included (A), management and outcome features (B). Abbreviations: COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, IV for intravenous, SAPS Simplified Acute Physiology Score, AV atrioventricular
A | |
Patients characteristics | (n = 4405) |
Age: mean ± SD | 65 ± 16 |
Gender male: n (%) | 2866 (65) |
SAPS2 (mean ± SD) | 46 ± 22 |
Coexisting condition or risk factors: n (%) | |
Diabetes | 580 (14) |
High blood pressure | 938 (21) |
Cancer and hematological malignancies | 402 (9) |
COPD and chronic respiratory failure | 413 (9) |
HIV | 140 (3) |
IV drug abuse | 135 (3) |
Dialysis dependent chronic kidney disease | 133 (3) |
Liver cirrhosis | 206 (5) |
Intra cardiac material: n (%) | 595 (14) |
Prosthetic valve | 527 (12) |
Pace maker and/or intra-cardiac defibrillator | 160 (4) |
Congenital cardiopathy: n (%) | 62 (1) |
Pathogens: n (%) | |
Staphylococcus sp. | 1404 (32) |
Streptococcus sp. (except S. pneumoniae) | 774 (18) |
Enterococcus sp. | 184 (4) |
Streptococcus pneumoniae | 96 (2) |
Pseudomonas aeruginosa | 124 (3) |
Intra cellular | 269 (6) |
Candida sp. | 122 (3) |
HACEK and Enterobacteriacceae | 354 (8) |
B | |
Patients management and outcomes | (n = 4405) |
Surgery: n (%) | 1502 (34) |
Acute respiratory failure: n (%) | 2899 (66) |
Mechanical ventilation | |
Invasive | 2521 (57) |
Noninvasive | 400 (9) |
Invasive ventilation duration: days (median (IQRs)) | 5 (2–13) |
Renal replacement therapy: n (%) | 1053 (24) |
Acute circulatory failure: n (%) | 2409 (55) |
Neurological complication: n (%) | 780 (18) |
Ischemic stroke | 459 (10) |
Intracranial bleeding | 228 (5) |
Meningitis | 132 (3) |
Cerebral abscess | 69 (2) |
Embolic complications (except neurological): n (%) | 128 (2.9) |
Acute limb ischemia | 93 (2.1) |
Splenic infarction | 20 (0.5) |
Kidney infarction | 16 (0.4) |
Liver infarction | 5 (0.1) |
Secondary infectious location (except neurological): n (%) | 246 (5.6) |
Septic arthritis | 100 (2.3) |
Splenic abscess | 20 (0.5) |
Kidney abscess | 23 (0.5) |
Liver abscess | 17 (0.4) |
Psoas abscess | 11 (0.2) |
Spondylodiscitis | 23 (0.5) |
Pulmonary abscess | 72 (1.6) |
High grade AV block | 258 (6) |
Death in ICU: n (%) | 1168 (26) |
Death in hospital: n (%) | 1403 (32) |
Length of stay in ICU: days (median (IQRs)) | 6 (3–13) |
Length of stay in hospital: days (median (IQRs) | 19 (8–38) |