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Table 2  Advantages and disadvantages of most common configurations of membrane lungs for CO2 retention applications

From: Physiological and Technical Considerations of Extracorporeal CO2 Removal

 

Stacked

Wound

Advantages

−Low pressure drop through higher permeability in flow direction

−Unidirectional flow

−Increased convectional gas transfer through cross-layered fiber arrangement

−Countercurrent flow possible

Disadvantages

−Inhomogeneous wash out of the corners and higher risk of thrombus formation

−Allows only crosscurrent flow

−Prone to clogging through washed in debris due to its smaller cross-sectional area

−Mostly long fibers and long flow path

Examples

−iLA (Novalung, Germany)

−Quadrox series (Maquet, Germany)

−Hilite product line (Medos Medizintechnik AG, Germany)

−CAPIOX oxygenator (Terumo, Japan)