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Table 1 Demographics and baseline clinical characteristics of enrolled patients

From: Early nasal high-flow versus Venturi mask oxygen therapy after lung resection: a randomized trial

Characteristic   HFNC
(n = 47)
Venturi mask
(n = 48)
Age, years   66 ± 10 68 ± 9
Female sex n (%) 20 (43) 21 (48)
Height, cm   165 ± 9 166 ± 9
Weight, kg   72 ± 14 74 ± 15
Body mass index, kg/m2   26 ± 4 27 ± 4
American Society of Anesthesiologist physical status n (%)   
 I   1 (2) 2 (4)
 II   33 (70) 31 (75)
 III   13 (28) 15 (21)
Comorbidities n (%)   
 Induction therapy   6 (13) 6 (13)
 History of cardiac failure   4 (9) 7 (15)
 History of ischemic heart disease   5 (11) 11 (23)
 Chronic obstructive pulmonary disease¶   25 (53) 32 (67)
 Pulmonary infections in the preceding month   12 (26) 11 (23)
 Active smoking   23 (49) 28 (58)
 Diabetes   4 (9) 7 (15)
Preoperative respiratory function
 FEV1, liters   2.2 ± 0.7 2.2 ± 0.7
 Forced vital capacity, liters   3.2 ± 0.9 3.3 ± 0.8
 Tiffenau index, %   72 ± 11 70 ± 10
Preoperative arterial blood gases
 PaO2, mmHg   85 ± 10 83 ± 10
 PaCO2, mmHg   37 ± 3 37 ± 3
 Patients with PaCO2 ≥ 45 mmHg n (%) 0 0
Side of surgery n (%)7   
 Right   30 (64) 29 (61)
 Left   17 (36) 19 (39)
Site of surgery n (%)  
 Upper lobe   24 (51) 28 (59)
 Middle lobe   3 (6) 5 (10)
 Lower lobe   20 (42) 15 (31)
Intraoperative tidal volume
 During two-lung ventilation
  ml   375 (350–450) 425 (369–456)
  ml/kg of predicted body weight   6.7 (6.4–7) 6.9 (6.5–7.3)
 During one-lung ventilation
  ml   300 (263–325) 313 (250–350)
  ml/kg of predicted body weight   5 (4.9–5.2) 5 (4.9–5.2)
Duration of mechanical ventilation, minutes   215 ± 59 222 ± 119
Duration of surgery, minutes   175. ± 66 172 ± 56
Intraoperative blood loss, ml   50 (0–200) 90 (0–163)
Intraoperative crystalloids, ml   900 (500–1500) 650 (500–1000)
Post-surgical management* n (%)   
  Post-anesthesia care unit   42 (89) 39 (81)
   Length of PACU stay, hours   6 (5–7) 6 (5–7)
  Intensive care unit   5 (11) 9 (19)
   Length of ICU stay, days   1 (1–3) 1 (1–3)
  1. Data are displayed as mean ± standard deviation or median (interquartile range), if not otherwise specified
  2. HFNC high-flow nasal cannula, PaCO2 arterial partial pressure of carbon dioxide, PaO2 arterial partial pressure of oxygen
  3. ¶Defined on the basis of the GOLD definitions [41]
  4. *The decision on whether the patient had to be transferred to the post-anesthesia or intensive care unit after extubation was taken by the attending anesthesiologist, who was aware of patient’s inclusion in the trial but not of the randomization arm