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Table 1 Demographics and baseline clinical characteristics of enrolled patients

From: Early nasal high-flow versus Venturi mask oxygen therapy after lung resection: a randomized trial

Characteristic

 

HFNC

(n = 47)

Venturi mask

(n = 48)

Age, years

 

66 ± 10

68 ± 9

Female sex

n (%)

20 (43)

21 (48)

Height, cm

 

165 ± 9

166 ± 9

Weight, kg

 

72 ± 14

74 ± 15

Body mass index, kg/m2

 

26 ± 4

27 ± 4

American Society of Anesthesiologist physical status

n (%)

  

 I

 

1 (2)

2 (4)

 II

 

33 (70)

31 (75)

 III

 

13 (28)

15 (21)

Comorbidities

n (%)

  

 Induction therapy

 

6 (13)

6 (13)

 History of cardiac failure

 

4 (9)

7 (15)

 History of ischemic heart disease

 

5 (11)

11 (23)

 Chronic obstructive pulmonary disease¶

 

25 (53)

32 (67)

 Pulmonary infections in the preceding month

 

12 (26)

11 (23)

 Active smoking

 

23 (49)

28 (58)

 Diabetes

 

4 (9)

7 (15)

Preoperative respiratory function

 FEV1, liters

 

2.2 ± 0.7

2.2 ± 0.7

 Forced vital capacity, liters

 

3.2 ± 0.9

3.3 ± 0.8

 Tiffenau index, %

 

72 ± 11

70 ± 10

Preoperative arterial blood gases

 PaO2, mmHg

 

85 ± 10

83 ± 10

 PaCO2, mmHg

 

37 ± 3

37 ± 3

 Patients with PaCO2 ≥ 45 mmHg

n (%)

0

0

Side of surgery

n (%)7

  

 Right

 

30 (64)

29 (61)

 Left

 

17 (36)

19 (39)

Site of surgery

n (%)

 

 Upper lobe

 

24 (51)

28 (59)

 Middle lobe

 

3 (6)

5 (10)

 Lower lobe

 

20 (42)

15 (31)

Intraoperative tidal volume

 During two-lung ventilation

  ml

 

375 (350–450)

425 (369–456)

  ml/kg of predicted body weight

 

6.7 (6.4–7)

6.9 (6.5–7.3)

 During one-lung ventilation

  ml

 

300 (263–325)

313 (250–350)

  ml/kg of predicted body weight

 

5 (4.9–5.2)

5 (4.9–5.2)

Duration of mechanical ventilation, minutes

 

215 ± 59

222 ± 119

Duration of surgery, minutes

 

175. ± 66

172 ± 56

Intraoperative blood loss, ml

 

50 (0–200)

90 (0–163)

Intraoperative crystalloids, ml

 

900 (500–1500)

650 (500–1000)

Post-surgical management*

n (%)

  

  Post-anesthesia care unit

 

42 (89)

39 (81)

   Length of PACU stay, hours

 

6 (5–7)

6 (5–7)

  Intensive care unit

 

5 (11)

9 (19)

   Length of ICU stay, days

 

1 (1–3)

1 (1–3)

  1. Data are displayed as mean ± standard deviation or median (interquartile range), if not otherwise specified
  2. HFNC high-flow nasal cannula, PaCO2 arterial partial pressure of carbon dioxide, PaO2 arterial partial pressure of oxygen
  3. ¶Defined on the basis of the GOLD definitions [41]
  4. *The decision on whether the patient had to be transferred to the post-anesthesia or intensive care unit after extubation was taken by the attending anesthesiologist, who was aware of patient’s inclusion in the trial but not of the randomization arm
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