Association between autoimmune disease and 30-day mortality, accounting for chronic DMARD and prednisone use | Sepsis cohort | Septic shock cohort | ||
---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
All potential confounders adjusteda | ||||
No autoimmune disease presence | ||||
No chronic DMARD/prednisone usage | 1.00 | Reference | 1.00 | Reference |
Autoimmune disease presence | ||||
No chronic DMARD or prednisone usage | 0.82 (0.58–1.16) | 0.272 | 0.76 (0.50–1.14) | 0.186 |
Chronic DMARD or prednisone usage | 0.89 (0.65–1.20) | 0.452 | 0.87 (0.62–1.22) | 0.428 |
SOFA score adjusted | ||||
No autoimmune disease presence | ||||
No chronic DMARD/prednisone usage | 1.00 | Reference | 1.00 | Reference |
Autoimmune disease presence | ||||
No chronic DMARD or prednisone usage | 0.80 (0.57–1.11) | 0.190 | 0.73 (0.49–1.07) | 0.114 |
Chronic DMARD or prednisone usage | 0.84 (0.62–1.12) | 0.231 | 0.77 (0.55–1.07) | 0.121 |