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Table 3 Analysis of the impact of potential confounders of the autoimmune disease-30-day mortality association

From: The association between autoimmune disease and 30-day mortality among sepsis ICU patients: a cohort study

Adjusting for confounders of the association between autoimmune disease and 30-day mortality OR (95% CI) P value Magnitude of confounding
No confounders adjusted (“crude”) 0.71 (0.58–0.86) < 0.001
Age adjusted 0.74 (0.60–0.90) 0.003 − 4.46%
Sex adjusted 0.71 (0.60–0.86) < 0.001 − 0.31%
Race adjusted 0.71 (0.58–0.87) < 0.001 − 0.93%
Documented bacteremia adjusted 0.68 (0.56–0.83) < 0.001 4.41%
Infection site adjusted 0.72 (0.56–0.83) 0.001 − 1.39%
SOFA score adjusted 0.81 (0.65–1.00) 0.051 − 12.34%
Elixhauser comorbidity index adjusted 0.71 (0.57–0.86) < 0.001 0.26%
DMARD or prednisone usage adjusted 0.66 (0.54–0.81) < 0.001 7.58%
ICU care unit adjusted 0.71 (0.58–0.86) < 0.001 0.10%
  1. Magnitude of confounding = (ORcrude − ORadjusted)/ORadjusted
  2. OR odds ratio, CI confidence interval, SOFA Sequential Organ Failure Assessment, DMARD disease-modifying antirheumatic drug, ICU intensive care unit