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Table 4 Risk factors for N-CLABSI in ICU patients (logistic regression)

From: The clinical impacts and risk factors for non-central line-associated bloodstream infection in 5046 intensive care unit patients: an observational study based on electronic medical records

Variables*

Univariate analysis

Multivariate analysis

OR (95% CI)

p value

Adjusted OR (95% CI)

p value

Age (years)

0.988 (0.980–0.997)

0.012

1.004 (0.993–1.016)

0.431

Sex (male)

1.322 (0.930–1.880)

0.120

  

APACHE II score on ICU admission

1.032 (1.010–1.050)

0.002

1.010 (0.986–1.034)

0.411

Chronic underlying diseases

1.033 (0.731–1.460)

0.853

  

Disorder of consciousness

1.443 (0.903–2.309)

0.125

  

Gastrointestinal bleeding

2.189 (1.409–3.399)

< 0.001

2.295 (1.377–3.824)

0.001

Trauma

1.390 (0.926–2.087)

0.112

2.521 (1.573–4.040)

< 0.001

Immunological diseases

0.706 (0.430–1.160)

0.171

  

Organ transplantation

0.871 (0.507–1.494)

0.615

  

Multiple organ failure

2.169 (1.562–3.011)

< 0.001

1.093 (0.734–1.627)

0.663

Shock

2.708 (1.959–3.743)

< 0.001

1.005 (0.683–1.479)

0.979

Pancreatitis

5.923 (4.268–8.220)

< 0.001

3.445 (2.239–5.300)

< 0.001

ARDS

4.180 (2.686–6.503)

< 0.001

1.673 (0.982–2.850)

0.058

Surgical operation

2.117 (1.446–3.098)

< 0.001

1.815 (1.186–2.776)

0.006

Intravascular catheters

6.078 (3.558–10.384)

< 0.001

2.934 (1.649–5.221)

< 0.001

Organ biopsy

1.256 (0.841–1.875)

0.265

  

MV

1.160 (0.664–2.024)

0.602

  

UC

0.621 (0.322–1.198)

0.155

  

MDRO positive

1.481 (1.072–2.046)

0.017

0.732 (0.500–1.069)

0.107

Sepsis

4.460 (3.042–6.538)

< 0.001

1.693 (1.088–2.633)

0.020

Pneumonia

1.946 (1.376–2.754)

< 0.001

1.528 (1.025–2.277)

0.038

IAI

15.185 (10.873–21.206)

< 0.001

8.369 (5.630–12.440)

< 0.001

HAIs other than NBSI, pneumonia and IAI

3.619 (2.135–6.135)

< 0.001

3.888 (2.087–7.244)

< 0.001

  1. BSI, bloodstream infection; N-CLABSI, non-central line-associated bloodstream infection; ICU, intensive care unit; OR, odds ratio; APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; MV, mechanical ventilation; UC, urinary catheter; MDRO, multidrug-resistant organism; IAI, intraabdominal infection; HAI, healthcare-associated infection
  2. *The variables selected into the multivariate logistic regression model are shown in italics
  3. Variables were analyzed by univariate logistic regression models. Parameters with p < 0.1 are shown in italics
  4. Variables were analyzed by a multiple logistic regression model. Parameters with statistical significance (p < 0.05) are shown in italics