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Table 3 Prediction performance of the reference and machine learning models in the test set

From: Emergency department triage prediction of clinical outcomes using machine learning models

Outcome and model

AUC

P value*

NRI†

P value†

Sensitivity

Specificity

PPV

NPV

Critical care outcome

 Reference model

0.74 (0.72–0.75)

Reference

Reference

Reference

0.50 (0.47–0.53)

0.86 (0.82–0.87)

0.07 (0.05–0.08)

0.988 (0.988–0.988)

 Lasso regression

0.84 (0.83–0.85)

< 0.001

0.39 (0.32–0.46)

< 0.001

0.75 (0.72–0.78)

0.77 (0.75–0.80)

0.06 (0.06–0.07)

0.993 (0.993–0.994)

 Random forest

0.85 (0.84–0.87)

< 0.001

0.07 (0.003–0.14)

0.04

0.86 (0.83–0.88)

0.68 (0.68–0.71)

0.05 (0.05–0.06)

0.996 (0.996–0.996)

 Gradient boosted decision tree

0.85 (0.83–0.86)

< 0.001

0.32 (0.25–0.38)

< 0.001

0.75 (0.73–0.79)

0.77 (0.75–0.80)

0.06 (0.06–0.07)

0.993 (0.993–0.994)

 Deep neural network

0.86 (0.85–0.87)

< 0.001

0.73 (0.67–0.79)

< 0.001

0.80 (0.77–0.83)

0.76 (0.73–0.78)

0.06 (0.06–0.07)

0.995 (0.994–0.995)

Hospitalization outcome

 Reference model

0.69 (0.68–0.69)

Reference

Reference

Reference

0.87 (0.86–0.87)

0.42 (0.39–0.43)

0.23 (0.22–0.23)

0.94 (0.94–0.94)

 Lasso regression

0.81 (0.80–0.81)

< 0.001

0.53 (0.50–0.55)

< 0.001

0.71 (0.70–0.72)

0.76 (0.75–0.77)

0.36 (0.35–0.37)

0.93 (0.93–0.93)

 Random forest

0.81 (0.81–0.82)

< 0.001

0.66 (0.63–0.68)

< 0.001

0.77 (0.76–0.78)

0.71 (0.70–0.72)

0.34 (0.33–0.35)

0.94 (0.94–0.94)

 Gradient boosted decision tree

0.82 (0.82–0.83)

< 0.001

0.63 (0.61–0.66)

< 0.001

0.75 (0.73–0.76)

0.75 (0.74–0.76)

0.37 (0.36–0.38)

0.94 (0.94–0.94)

 Deep neural network

0.82 (0.82–0.83)

< 0.001

0.68 (0.65–0.70)

< 0.001

0.79 (0.78–0.80)

0.71 (0.69–0.72)

0.35 (0.34–0.36)

0.95 (0.94–0.95)

  1. Abbreviations: AUC area under the curve, NRI net reclassification improvement, PPV positive predictive value, NPV negative predictive value
  2. *P value was calculated to compare the area under the receiver-operating-characteristics curve (AUC) of the reference model with that of each machine learning model
  3. †We used continuous NRI and its P value